Neuroinflammatio
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Neuroinflammatio est notio hodierna inflammationis textuum nervorum et responsum eius mutationibus homoeostasis[1]. Cellulae systematis immunitatis, ut cellulae microgliales, effectus exercent.
In nonnullis morbis neurodegenerativis, ut morbo Alzheimeriano, valores cytokinorum elevatae sunt.
Morbus Alzheimerianus
recensere Conferatur pagina principalis Morbus Alzheimerianus.
In morbo Alzheimeriano pluria cytokina cum valoribus eorum elevatis conspicuis videntur: eotaxinum, interleukina (IL) IL-1ra, IL-4, IL-4, IL-7, IL-8, IL-9, IL-10, IL-15, tumoris necrosis factor (TNF, antea: TNF-α)[2].
Notae
recensere- ↑ Ransohoff R. M., Schafer D., Vincent A., Blachère N. E., Bar-Or A. (2015). "Neuroinflammation: Ways in Which the Immune System Affects the Brain". Neurotherapeutics 12 (4): 896-909
- ↑ Taipa R., das Neves S. P., Sousa A. L., Fernandes J., Pinto C., Correia A. P., Santos E., Pinto P. S., Carneiro P., Costa P., Santos D., Alonso I., Palha J., Marques F., Cavaco S., Sousa N. (2019). "Proinflammatory and anti-inflammatory cytokines in the CSF of patients with Alzheimer's disease and their correlation with cognitive decline". Neurobiology of aging 76: 125-32