Status: Bibliographieeintrag
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| Verfasst von: | Domonkos, Lilla [VerfasserIn]  |
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| | Yusenko, Maria [VerfasserIn] |
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| | Kovacs, Gyula [VerfasserIn] |
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| | Peterfi, Lehel [VerfasserIn] |
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| Titel: | Impact of cellular morphology and three-tiered nuclear grade on progression of conventional renal cell carcinoma |
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| Verf.angabe: | Lilla Domonkos, Maria Yusenko, Gyula Kovacs, Lehel Peterfi |
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| E-Jahr: | 2024 |
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| Jahr: | March 20, 2024 |
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| Umfang: | 5 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Zuerst veröffentlicht: 19. Dezember 2023 ; Gesehen am 22.03.2024 |
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| Titel Quelle: | Enthalten in: Journal of clinical pathology |
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| Ort Quelle: | London : BMJ Publ. Group, 1947 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 77(2024), 4 vom: März, Seite 246-250 |
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| ISSN Quelle: | 1472-4146 |
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| Abstract: | Aims and methods The aims of this study were to evaluate the prognostic impact of cytomorphology and three-tiered grading on tumour-free survival of patients with conventional renal cell carcinoma (cRCC). Formalin-fixed, paraffin-embedded samples from 710 patients were assessed and the results were evaluated according to the clinical data. - Results Kaplan-Meier regression model showed that 90.9% of patients with clear cell, and 50.9% with pure eosinophilic cRCC were free of metastasis during follow-up. The three-triered grading showed a good correlation with progression as 95.2% of patients with of G1 tumours, 66.1% with G2 tumours and only 25.3% with G3 tumours were tumour free (p<0.001). The grading was correlated with cytomorphology and coagulation necrosis. In multivariate analysis, tumour grade and stage were independent prognostic markers (p<0.001). - Conclusions The three-tiered grading predicts the progression of cRCC irrespectively of cytomorphology. However, the cytomorphology and necrosis show a good correlation with three-tiered grading in estimate disease progression. |
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| DOI: | doi:10.1136/jcp-2023-209094 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1136/jcp-2023-209094 |
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| | Volltext: https://jcp.bmj.com/content/77/4/246 |
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| | DOI: https://doi.org/10.1136/jcp-2023-209094 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Histology |
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| | Kidney Neoplasms |
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| | Morphological and Microscopic Findings |
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| | Urologic Neoplasms |
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| K10plus-PPN: | 1884067360 |
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| Verknüpfungen: | → Zeitschrift |
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Impact of cellular morphology and three-tiered nuclear grade on progression of conventional renal cell carcinoma / Domonkos, Lilla [VerfasserIn]; March 20, 2024 (Online-Ressource)
69194386
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