| |  Online-Ressource |
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| Verfasst von: | Ramírez-Martín, Almudena [VerfasserIn]  |
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| | Sirignano, Lea [VerfasserIn] |
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| | Streit, Fabian [VerfasserIn] |
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| | Foo, Jerome Clifford [VerfasserIn] |
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| | Forstner, Andreas J. [VerfasserIn] |
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| | Frank, Josef [VerfasserIn] |
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| | Nöthen, Markus Maria [VerfasserIn] |
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| | Strohmaier, Jana [VerfasserIn] |
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| | Witt, Stephanie [VerfasserIn] |
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| | Mayoral-Cleries, Fermin [VerfasserIn] |
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| | Moreno-Küstner, Berta [VerfasserIn] |
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| | Rietschel, Marcella [VerfasserIn] |
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| | Guzman-Parra, Jose [VerfasserIn] |
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| Titel: | Impulsivity, decision-making, and risk behavior in bipolar disorder and major depression from bipolar multiplex families |
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| Titelzusatz: | original article |
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| Verf.angabe: | Almudena Ramírez-Martín, Lea Sirignano, Fabian Streit, Jerome C Foo, Andreas J Forstner, Josef Frank, Markus M Nöthen, Jana Strohmaier, Stephanie H Witt, Fermin Mayoral-Cleries, Berta Moreno-Küstner, Marcella Rietschel, Jose Guzmán-Parra |
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| E-Jahr: | 2023 |
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| Jahr: | 18 December 2023 |
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| Umfang: | 11 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 13.02.2024 |
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| Titel Quelle: | Enthalten in: Brain and behavior |
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| Ort Quelle: | Malden, Mass. : Wiley, 2011 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 14(2023), 2, Artikel-ID e3337, Seite 1-11 |
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| ISSN Quelle: | 2162-3279 |
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| Abstract: | Objectives Bipolar disorder (BD) and major depressive disorder (MDD) are characterized by specific alterations of mood. In both disorders, alterations in cognitive domains such as impulsivity, decision-making, and risk-taking have been reported. Identification of similarities and differences of these domains in BD and MDD could give further insight into their etiology. The present study assessed impulsivity, decision-making, and risk-taking behavior in BD and MDD patients from bipolar multiplex families. Methods Eighty-two participants (BD type I, n = 25; MDD, n = 26; healthy relatives (HR), n = 17; and healthy controls (HC), n = 14) underwent diagnostic interviews and selected tests of a cognitive battery assessing neurocognitive performance across multiple subdomains including impulsivity (response inhibition and delay aversion), decision-making, and risk behavior. Generalized estimating equations (GEEs) were used to analyze whether the groups differed in the respective cognitive domains. Results Participants with BD and MDD showed higher impulsivity levels compared to HC; this difference was more pronounced in BD participants. BD participants also showed lower inhibitory control than MDD participants. Overall, suboptimal decision-making was associated with both mood disorders (BD and MDD). In risk-taking behavior, no significant impairment was found in any group. Limitations As sample size was limited, it is possible that differences between BD and MDD may have escaped detection due to lack of statistical power. Conclusions Our findings show that alterations of cognitive domains—while present in both disorders—are differently associated with BD and MDD. This underscores the importance of assessing such domains in addition to mere diagnosis of mood disorders. |
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| DOI: | doi:10.1002/brb3.3337 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1002/brb3.3337 |
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| | kostenfrei: Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/brb3.3337 |
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| | DOI: https://doi.org/10.1002/brb3.3337 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | bipolar disorder |
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| | bipolar multiplex families |
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| | decision-making |
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| | impulsivity |
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| | major depression disorder |
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| | risk behavior |
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| K10plus-PPN: | 1880596784 |
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| Verknüpfungen: | → Zeitschrift |
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Impulsivity, decision-making, and risk behavior in bipolar disorder and major depression from bipolar multiplex families / Ramírez-Martín, Almudena [VerfasserIn]; 18 December 2023 (Online-Ressource)
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