Online-Ressource | |
Verfasst von: | Kästner, Lena [VerfasserIn] |
Boda-Heggemann, Judit [VerfasserIn] | |
Fanslau, Hannah [VerfasserIn] | |
Xie, Jingyang [VerfasserIn] | |
Schweikard, Achim [VerfasserIn] | |
Giordano, Frank Anton [VerfasserIn] | |
Blanck, Oliver [VerfasserIn] | |
Rudic, Boris [VerfasserIn] | |
Titel: | Electroanatomical mapping after cardiac radioablation for treatment of incessant electrical storm |
Titelzusatz: | a case report from the RAVENTA trial |
Verf.angabe: | Lena Kaestner, Judit Boda-Heggemann, Hannah Fanslau, Jingyang Xie, Achim Schweikard, Frank A. Giordano, Oliver Blanck, Boris Rudic |
E-Jahr: | 2023 |
Jahr: | 12 September 2023 |
Umfang: | 7 S. |
Fussnoten: | Gesehen am 11.12.2023 |
Titel Quelle: | Enthalten in: Strahlentherapie und Onkologie |
Ort Quelle: | Berlin : Springer Medizin, 1997 |
Jahr Quelle: | 2023 |
Band/Heft Quelle: | 199(2023), 11, Seite 1018-1024 |
ISSN Quelle: | 1439-099X |
Abstract: | Background Electroanatomical mapping (EAM)-guided stereotactic arrhythmia radioablation (STAR) is a novel noninvasive therapy option for patients with monomorphic ventricular tachycardia (VT) refractory to antiarrhythmic drugs and/or urgent catheter ablation (CA). Data on success rates in an emergency situation such as electrical storm (ES) are rare. We present a case of a patient with an initially very poor life expectancy after extensive myocardial infarction with therapy-resistant ES, not amendable for further antiarrhythmic drug therapy, implantable cardioverter-defibrillator implantation, or repeated CA who was introduced to the radiation oncology department for emergency STAR as a bail-out therapy. - Methods Target volume definition and transfer from EAM to CT were validated and quality assured with a semi-automatic, dedicated visualization tool (CARDIO-RT). Emergency STAR was performed with 25 Gy in the framework of the RAVENTA study. The VT burden gradually decreased after STAR; however, a second VT morphology occurred, which was successfully treated with EAM-guided CA 12 days after STAR. - Results The second EAM-guided CA showed areas of low voltage in the irradiated segments, indicating a precise targeting and early functional response to STAR. The patient remained free of any VT recurrence or any radiation-related toxicities and in good general condition during the recent follow-up of 18 months. - Conclusion The case highlights the possible approach, caveats, difficulties, and prognosis of a patient severely affected by therapy-resistant VT in whom CA could not lead to VT suppression. Further studies of putative mechanisms of STAR in the acute and chronic phase of this novel therapy are warranted. |
DOI: | doi:10.1007/s00066-023-02136-z |
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DOI: https://doi.org/10.1007/s00066-023-02136-z | |
Datenträger: | Online-Ressource |
Sprache: | eng |
K10plus-PPN: | 1873044526 |
Verknüpfungen: | → Zeitschrift |