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Verfasst von:Kästner, Lena [VerfasserIn]   i
 Boda-Heggemann, Judit [VerfasserIn]   i
 Fanslau, Hannah [VerfasserIn]   i
 Xie, Jingyang [VerfasserIn]   i
 Schweikard, Achim [VerfasserIn]   i
 Giordano, Frank Anton [VerfasserIn]   i
 Blanck, Oliver [VerfasserIn]   i
 Rudic, Boris [VerfasserIn]   i
Titel:Electroanatomical mapping after cardiac radioablation for treatment of incessant electrical storm
Titelzusatz:a case report from the RAVENTA trial
Verf.angabe:Lena Kaestner, Judit Boda-Heggemann, Hannah Fanslau, Jingyang Xie, Achim Schweikard, Frank A. Giordano, Oliver Blanck, Boris Rudic
E-Jahr:2023
Jahr:12 September 2023
Umfang:7 S.
Fussnoten:Gesehen am 11.12.2023
Titel Quelle:Enthalten in: Strahlentherapie und Onkologie
Ort Quelle:Berlin : Springer Medizin, 1997
Jahr Quelle:2023
Band/Heft Quelle:199(2023), 11, Seite 1018-1024
ISSN Quelle:1439-099X
Abstract:Background Electroanatomical mapping (EAM)-guided stereotactic arrhythmia radioablation (STAR) is a novel noninvasive therapy option for patients with monomorphic ventricular tachycardia (VT) refractory to antiarrhythmic drugs and/or urgent catheter ablation (CA). Data on success rates in an emergency situation such as electrical storm (ES) are rare. We present a case of a patient with an initially very poor life expectancy after extensive myocardial infarction with therapy-resistant ES, not amendable for further antiarrhythmic drug therapy, implantable cardioverter-defibrillator implantation, or repeated CA who was introduced to the radiation oncology department for emergency STAR as a bail-out therapy. - Methods Target volume definition and transfer from EAM to CT were validated and quality assured with a semi-automatic, dedicated visualization tool (CARDIO-RT). Emergency STAR was performed with 25 Gy in the framework of the RAVENTA study. The VT burden gradually decreased after STAR; however, a second VT morphology occurred, which was successfully treated with EAM-guided CA 12 days after STAR. - Results The second EAM-guided CA showed areas of low voltage in the irradiated segments, indicating a precise targeting and early functional response to STAR. The patient remained free of any VT recurrence or any radiation-related toxicities and in good general condition during the recent follow-up of 18 months. - Conclusion The case highlights the possible approach, caveats, difficulties, and prognosis of a patient severely affected by therapy-resistant VT in whom CA could not lead to VT suppression. Further studies of putative mechanisms of STAR in the acute and chronic phase of this novel therapy are warranted.
DOI:doi:10.1007/s00066-023-02136-z
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 DOI: https://doi.org/10.1007/s00066-023-02136-z
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1873044526
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