Online-Ressource | |
Verfasst von: | Bärtsch, Marc-Andrea [VerfasserIn] |
Nolan, Garry [VerfasserIn] | |
Hickey, John W. [VerfasserIn] | |
Titel: | Multicellular modules as clinical diagnostic and therapeutic targets |
Verf.angabe: | Marc-A. Baertsch, Garry P. Nolan, John W. Hickey |
Jahr: | 2022 |
Umfang: | 10 S. |
Fussnoten: | Available online 3 December 2021 ; Gesehen am 30.05.2022 |
Titel Quelle: | Enthalten in: Trends in cancer |
Ort Quelle: | Amsterdam : Elsevier, 2015 |
Jahr Quelle: | 2022 |
Band/Heft Quelle: | 8(2022), 3, Seite 164-173 |
ISSN Quelle: | 2405-8025 |
Abstract: | The complex determinants of health and disease can be determined when approached as a system of interactions of biological agents at different scales. Similar to the physicochemical properties that govern nucleic acids and proteins, there should be a finite set of rules that dictate the behavior of cells to form tissues. Thus, the occurrence of disease can be seen as flaws in processes that are governed by rules pertaining to multicellular structures. Multiplexed imaging is a technology that connects information that bridges multiple biological scales (i.e., molecules, cells, and tissues) and enables elucidation of rules associated with the formation of multicellular structures. Uncovering important multicellular structures associated with disease will propel a wave of development of new categories of diagnostics and therapeutics. |
DOI: | doi:10.1016/j.trecan.2021.11.004 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt. Volltext ; Verlag: https://doi.org/10.1016/j.trecan.2021.11.004 |
Volltext: https://www.sciencedirect.com/science/article/pii/S2405803321002302 | |
DOI: https://doi.org/10.1016/j.trecan.2021.11.004 | |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | cancer immunotherapy |
diagnostics | |
multicellular structures | |
multiplexed tissue imaging | |
spatial biology | |
therapeutics | |
K10plus-PPN: | 1805199145 |
Verknüpfungen: | → Zeitschrift |