| |  Online-Ressource |
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| Verfasst von: | Schiefer, Sabine [VerfasserIn]  |
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| | Wirsik, Naita Maren [VerfasserIn] |
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| | Kalkum, Eva [VerfasserIn] |
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| | Seide, Svenja [VerfasserIn] |
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| | Nienhüser, Henrik [VerfasserIn] |
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| | Müller, Beat P. [VerfasserIn] |
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| | Billeter, Adrian [VerfasserIn] |
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| | Büchler, Markus W. [VerfasserIn] |
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| | Schmidt, Thomas [VerfasserIn] |
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| | Probst, Pascal [VerfasserIn] |
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| Titel: | Systematic review of prognostic role of blood cell ratios in patients with gastric cancer undergoing surgery |
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| Verf.angabe: | Sabine Schiefer, Naita Maren Wirsik, Eva Kalkum, Svenja Elisabeth Seide, Henrik Nienhüser, Beat Müller, Adrian Billeter, Markus W. Büchler, Thomas Schmidt and Pascal Probst |
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| E-Jahr: | 2022 |
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| Jahr: | 25 February 2022 |
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| Umfang: | 20 S. |
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| Fussnoten: | Gesehen am 06.04.2022 |
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| Titel Quelle: | Enthalten in: Diagnostics |
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| Ort Quelle: | Basel : MDPI, 2011 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 12(2022), 3, Artikel-ID 593, Seite 1-20 |
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| ISSN Quelle: | 2075-4418 |
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| Abstract: | Various blood cell ratios exist which seem to have an impact on prognosis for resected gastric cancer patients. The aim of this systematic review was to investigate the prognostic role of blood cell ratios in patients with gastric cancer undergoing surgery in a curative attempt. A systematic literature search in MEDLINE (via PubMed), CENTRAL, and Web of Science was performed. Information on survival and cut-off values from all studies investigating any blood cell ratio in resected gastric cancer patients were extracted. Prognostic significance and optimal cut-off values were calculated by meta-analyses and a summary of the receiver operating characteristic. From 2831 articles, 65 studies investigated six different blood cell ratios (prognostic nutritional index (PNI), lymphocyte to monocyte ratio (LMR), systemic immune-inflammation index (SII), monocyte to lymphocyte ratio (MLR), neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR)). There was a significant association for the PNI and NLR with overall survival and disease-free survival and for LMR and NLR with 5-year survival. The used cut-off values had high heterogeneity. The available literature is flawed by the use of different cut-off values hampering evidence-based patient treatment and counselling. This article provides optimal cut-off values recommendations for future research. |
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| DOI: | doi:10.3390/diagnostics12030593 |
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| URL: | kostenfrei: Volltext ; Verlag: https://doi.org/10.3390/diagnostics12030593 |
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| | kostenfrei: Volltext: https://www.mdpi.com/2075-4418/12/3/593 |
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| | DOI: https://doi.org/10.3390/diagnostics12030593 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | blood cell ratios |
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| | confounder |
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| | gastric cancer |
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| | prognostic studies |
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| K10plus-PPN: | 1797788434 |
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| Verknüpfungen: | → Zeitschrift |
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| Lokale URL UB: |  Zum Volltext |
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Systematic review of prognostic role of blood cell ratios in patients with gastric cancer undergoing surgery / Schiefer, Sabine [VerfasserIn]; 25 February 2022 (Online-Ressource)
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