| |  Online-Ressource |
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| Verfasst von: | Hasseli, Rebecca [VerfasserIn]  |
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| | Mueller-Ladner, Ulf [VerfasserIn] |
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| | Hoyer, Bimba F. [VerfasserIn] |
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| | Krause, Andreas [VerfasserIn] |
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| | Lorenz, Hanns-Martin [VerfasserIn] |
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| | Pfeil, Alexander [VerfasserIn] |
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| | Richter, Jutta [VerfasserIn] |
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| | Schäfer, Martin [VerfasserIn] |
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| | Schmeiser, Tim [VerfasserIn] |
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| | Strangfeld, Anja [VerfasserIn] |
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| | Schulze-Koops, Hendrik [VerfasserIn] |
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| | Voll, Reinhard E. [VerfasserIn] |
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| | Specker, Christof [VerfasserIn] |
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| | Regierer, Anne Constanze [VerfasserIn] |
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| Titel: | Older age, comorbidity, glucocorticoid use and disease activity are risk factors for COVID-19 hospitalisation in patients with inflammatory rheumatic and musculoskeletal diseases |
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| Verf.angabe: | Rebecca Hasseli, Ulf Mueller-Ladner, Bimba F. Hoyer, Andreas Krause, Hanns-Martin Lorenz, Alexander Pfeil, Jutta Richter, Martin Schäfer, Tim Schmeiser, Anja Strangfeld, Hendrik Schulze-Koops, Reinhard E. Voll, Christof Specker, Anne Constanze Regierer |
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| E-Jahr: | 2021 |
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| Jahr: | January 21, 2021 |
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| Teil: | volume:7 |
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| | year:2021 |
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| | number:1 |
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| Fussnoten: | Gesehen am 09.03.2021 |
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| Titel Quelle: | Enthalten in: RMD Open |
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| Ort Quelle: | London : BMJ Publishing Group, 2015 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 7(2021,1) Artikel-Nummer e001464, 8 Seiten |
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| ISSN Quelle: | 2056-5933 |
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| Abstract: | Introduction Whether patients with inflammatory rheumatic and musculoskeletal diseases (RMD) are at higher risk to develop severe courses of COVID-19 has not been fully elucidated. Aim of this analysis was to describe patients with RMD according to their COVID-19 severity and to identify risk factors for hospitalisation. - Methods Patients with RMD with PCR confirmed SARS-CoV-2 infection reported to the German COVID-19 registry from 30 March to 1 November 2020 were evaluated. Multivariable logistic regression was used to estimate ORs for hospitalisation due to COVID-19. - Results Data from 468 patients with RMD with SARS-CoV-2 infection were reported. Most frequent diagnosis was rheumatoid arthritis, RA (48%). 29% of the patients were hospitalised, 5.5% needed ventilation. 19 patients died. Multivariable analysis showed that age >65 years (OR 2.24; 95% CI 1.12 to 4.47), but even more>75 years (OR 3.94; 95% CI 1.86 to 8.32), cardiovascular disease (CVD; OR 3.36; 95% CI 1.5 to 7.55), interstitial lung disease/chronic obstructive pulmonary disease (ILD/COPD) (OR 2.79; 95% CI 1.2 to 6.49), chronic kidney disease (OR 2.96; 95% CI 1.16 to 7.5), moderate/high RMD disease activity (OR 1.96; 95% CI 1.02 to 3.76) and treatment with glucocorticoids (GCs) in dosages >5 mg/day (OR 3.67; 95% CI 1.49 to 9.05) were associated with higher odds of hospitalisation. Spondyloarthritis patients showed a smaller risk of hospitalisation compared with RA (OR 0.46; 95% CI 0.23 to 0.91). - Conclusion Age was a major risk factor for hospitalisation as well as comorbidities such as CVD, ILD/COPD, chronic kidney disease and current or prior treatment with GCs. Moderate to high RMD disease activity was also an independent risk factor for hospitalisation, underlining the importance of continuing adequate RMD treatment during the pandemic. |
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| DOI: | doi:10.1136/rmdopen-2020-001464 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1136/rmdopen-2020-001464 |
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| | Volltext: https://rmdopen.bmj.com/content/7/1/e001464 |
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| | DOI: https://doi.org/10.1136/rmdopen-2020-001464 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | arthritis |
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| | epidemiology |
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| | glucocorticoids |
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| K10plus-PPN: | 1750851903 |
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| Verknüpfungen: | → Zeitschrift |
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Older age, comorbidity, glucocorticoid use and disease activity are risk factors for COVID-19 hospitalisation in patients with inflammatory rheumatic and musculoskeletal diseases / Hasseli, Rebecca [VerfasserIn]; January 21, 2021 (Online-Ressource)
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