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| Titel: | Molecular structure and function of the tight junction |
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| Titelzusatz: | from basic mechanisms to clinical manifestations ; [... result of a Conference Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] |
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| Mitwirkende: | Fromm, Michael [Hrsg.]  |
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| Institutionen: | Conference Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations <2008, Berlin> |
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| Verf.angabe: | ed. by Michael Fromm ... |
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| Verlagsort: | Boston, Mass. |
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| Verlag: | Blackwell |
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| Jahr: | 2009 |
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| Umfang: | VIII, 346 S. |
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| Illustrationen: | Ill., graph. Darst. |
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| Format: | 25 cm |
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| Gesamttitel/Reihe: | Annals of the New York Academy of Sciences ; vol. 1165 |
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| Fussnoten: | Includes bibliographical references and index |
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| ISBN: | 1-57331-749-7 |
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| | 978-1-57331-749-8 |
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| Abstract: | Tight junctions: molecular structure meets function -- Molecular structure and function of the tight junction. Proceedings of an international conference dedicated to the memory of Shoichiro Tsukita. April 25-27, 2008. Berlin, Germany -- The life and work of Shoichiro Tsukita -- Mechanisms of outside-in signaling at the tight junction by junctional adhesion molecule A -- The oligomerization of the coiled coil-domain of occludin is redox sensitive -- Vertebrate animal models unravel physiological roles for zonula occludens tight junction adaptor proteins -- Structure and function of extracellular claudin domains -- Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function -- Molecular basis for cation selectivity in claudin-2-based pores -- The role of claudin-based tight junctions in morphogenesis -- Occludin phosphorylation in regulation of epithelial tight junctions -- Differential phosphorylation of occludin and tricellulin by CK2 and CK1 -- High-resolution analysis of barrier function -- Claudin-2-dependent changes in noncharged solute flux are mediated by the extracellular domains and require attachment to the PDZ-scaffold -- The tight junction protein cingulin regulates gene expression and RhoA signaling -- Modification of tight junction structure and permeability by nutritional means -- Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctions -- The tight junction protein ZO-2 blocks cell cycle progression and inhibits cyclin D1 expression -- Analysis of claudin genes in pediatric patients with Bartter's syndrome -- Mechanisms of epithelial cell shedding in the Mammalian intestine and maintenance of barrier function -- Cysteine mutagenesis to study the structure of claudin-2 paracellular pores -- Insights into driving forces and paracellular permeability from claudin-16 knockdown mouse -- Claudin function in the thick ascending limb of Henle's loop -- Cadherin-mediated regulation of tight junctions in stratifying epithelia -- Tight junctions and enteropathogenic E. coli -- Modulation of intestinal barrier properties by probiotics: role in reversing colitis -- Effect of probiotics on intestinal barrier function -- Probiotic therapy in radiation-induced intestinal injury and repair -- Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms -- Corticotropin-releasing hormone and mast cells in the regulation of mucosal barrier function in the human colon -- Tight junction proteins as channel formers and barrier builders -- Dynamic regulation of epithelial cell fate and barrier function by intercellular junctions -- Control of the blood-brain barrier by glucocorticoids and the cells of the neurovascular unit -- Regulation of intestinal electroneutral sodium absorption and the brush border Na+/H+ exchanger by intracellular calcium -- The role of the NHERF family of PDZ scaffolding proteins in the regulation of salt and water transport -- Regulation of the intestinal anion exchanger DRA (downregulated in adenoma) -- Barrier effects of nutritional factors -- Pathways of gliadin transport in celiac disease -- A new insight into pathophysiological mechanisms of zinc in diarrhea -- Mechanisms of diarrhea in inflammatory bowel diseases -- Epithelial tight junctions in intestinal inflammation -- Mechanisms of tight junction dysregulation in the SAMP1/YitFc model of Crohn's disease-like ileitis -- The role of JAM-A in inflammatory bowel disease: unrevealing the ties that bind -- No static at all -- Lymphoepithelial interactions: a new paradigm -- Metabolic stress evokes decreases in epithelial barrier function -- Enteral versus parenteral nutrition: effect on intestinal barrier function |
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| URL: | Verlagsangaben: http://www.loc.gov/catdir/enhancements/fy1003/2009499655-d.html |
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| | Cover: https://swbplus.bsz-bw.de/bsz308092996cov.jpg |
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| Schlagwörter: | (s)Tight junction |
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| Dokumenttyp: | Konferenzschrift |
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| Sprache: | eng |
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| RVK-Notation: | WE 5160 |
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| K10plus-PPN: | 603955959 |
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| Verknüpfungen: | → Übergeordnete Aufnahme |
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1-57331-749-7,978-1-57331-749-8
Molecular structure and function of the tight junction / Fromm, Michael [Hrsg.]; 2009
66771352
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