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Open Access
Peer-reviewed
Research Article
HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation
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Lucie Colineau ,
Contributed equally to this work with: Lucie Colineau, Angeline Rouers
Current address: Department of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, British Columbia, Canada
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, CNRS, ERL 8255, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France
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Angeline Rouers ,
Contributed equally to this work with: Lucie Colineau, Angeline Rouers
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, CNRS, ERL 8255, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France
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Takuya Yamamoto,
Affiliation Immunology Laboratory, Vaccine research center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, United States of America
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Yin Xu,
Affiliation The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
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Alejandra Urrutia,
Current address: Institut Pasteur, Centre d’Immunologie Humaine, F-75015, Paris, France
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, CNRS, ERL 8255, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France
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Hang-Phuong Pham,
Affiliations Sorbonne Universités UPMC Université Paris 06, UMRS 959, Immunology-Immunopathology-Immunotherapy (I3), Paris, France, INSERM, UMRS 959, Immunology-Immunopathology-Immunotherapy (I3), Paris, France, CNRS, FRE3632, Immunology-Immunopathology-Immunotherapy (I3), Paris, France
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Sylvain Cardinaud,
Current address: INSERM, U955, IMRB, Vaccine Research Institute, F-94010, Creteil, France
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, CNRS, ERL 8255, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France
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Assia Samri,
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, AP-HP, Hôpital Pitié-Salpêtière, Department of Immunology, Paris, France
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Karim Dorgham,
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, AP-HP, Hôpital Pitié-Salpêtière, Department of Immunology, Paris, France
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Pierre-Grégoire Coulon,
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, CNRS, ERL 8255, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France
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Rémi Cheynier,
Affiliations INSERM, U1016, Institut Cochin, Paris, France, CNRS, UMR8104, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Paris, France
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Anne Hosmalin,
Affiliations INSERM, U1016, Institut Cochin, Paris, France, CNRS, UMR8104, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Paris, France, AP-HP, Hôpital Cochin, Paris, France
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Eric Oksenhendler,
Affiliation Université Paris Diderot, Assistance Publique-Hôpitaux de Paris, Département d’Immunologie Clinique, Hôpital Saint-Louis, Paris, France
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Adrien Six,
Affiliations Sorbonne Universités UPMC Université Paris 06, UMRS 959, Immunology-Immunopathology-Immunotherapy (I3), Paris, France, INSERM, UMRS 959, Immunology-Immunopathology-Immunotherapy (I3), Paris, France, CNRS, FRE3632, Immunology-Immunopathology-Immunotherapy (I3), Paris, France
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Anthony D. Kelleher,
Affiliation The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
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John Zaunders,
Affiliation St. Vincent's Centre for Applied Medical Research, St. Vincent's Hospital, Sydney, Australia
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Richard A. Koup,
Affiliation Immunology Laboratory, Vaccine research center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, United States of America
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Brigitte Autran,
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, AP-HP, Hôpital Pitié-Salpêtière, Department of Immunology, Paris, France
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Arnaud Moris,
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, CNRS, ERL 8255, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, AP-HP, Hôpital Pitié-Salpêtière, Department of Immunology, Paris, France
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Stéphanie Graff-Dubois
* E-mail: [email protected]
Affiliations Sorbonne Universités, UPMC Université Paris 06, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, INSERM, U1135, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France, CNRS, ERL 8255, Center for Immunology and Microbial Infections—CIMI-Paris, Paris, France
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HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation
- Lucie Colineau,
- Angeline Rouers,
- Takuya Yamamoto,
- Yin Xu,
- Alejandra Urrutia,
- Hang-Phuong Pham,
- Sylvain Cardinaud,
- Assia Samri,
- Karim Dorgham,
- Pierre-Grégoire Coulon
- Published: October 26, 2015
- https://doi.org/10.1371/journal.pone.0140978
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