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[en] Modern single molecule fluorescence microscopy offers new, highly quantitative ways of studying the systems biology of cells while keeping the cells healthy and alive in their natural environment. In this context, a quantum optical technique, photon antibunching, has found a small niche in the continuously growing applications of single molecule techniques to small molecular complexes. Here, we review some of the most recent applications of photon antibunching in biophotonics, and we provide a guide for how to conduct photon antibunching experiments at the single molecule level by applying techniques borrowed from time-correlated single photon counting. We provide a number of new examples for applications of photon antibunching to the study of multichromophoric molecules and small molecular complexes
Journal
IEEE Journal of Selected Topics in Quantum Electronics; ISSN 1077-260X; 
; v. 13(4); p. 996
; v. 13(4); p. 996
[en] An introductory overview to the special issue papers on diffraction structural biology in this issue of the journal. An introductory overview to the special issue papers on diffraction structural biology in this issue of the journal
Journal
No abstract available
Journal
[en] This paper forms the introductory chapter to a book concerning the use of synchrotron radiation for investigation of the structure and mechanism of biological macromolecules. After a historical section, the physics of synchrotron radiation is summarized so that the most promising experiments may be extrapolated. Irradiated power and intensity, polarization and angular distribution, brilliance of a real source, and developments such as wigglers and undulators are briefly dealt with. The paper includes a tabulated compilation of proposed and operating machines in 1982, with some of their characteristics. (U.K.)
Source
Stuhrmann, H.B. (ed.) (European Molecular Biology Laboratory, Hamburg (Germany, F.R.)); 348 p; ISBN 0 12 674850 0; ; 1982; p. 1-21; Academic Press; London (UK)
; 1982; p. 1-21; Academic Press; London (UK)
No abstract available
Journal
No abstract available
Journal
Nuclear Instruments and Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment; ISSN 0168-9002; ; v. 467(PT2); [10 p.]
; v. 467(PT2); [10 p.]
[en] Understanding the mechanisms governing and regulating the emergence of structure and heterogeneity within cellular systems, such as the developing embryo, represents a multiscale challenge typifying current integrative biology research, namely, explaining the macroscale behaviour of a system from microscale dynamics. This review will focus upon modelling how cell-based dynamics orchestrate the emergence of higher level structure. After surveying representative biological examples and the models used to describe them, we will assess how developments at the scale of molecular biology have impacted on current theoretical frameworks, and the new modelling opportunities that are emerging as a result. We shall restrict our survey of mathematical approaches to partial differential equations and the tools required for their analysis. We will discuss the gap between the modelling abstraction and biological reality, the challenges this presents and highlight some open problems in the field. (invited article)
Journal
Nonlinearity (Print); ISSN 0951-7715; ; v. 21(11); p. R251-R290
; v. 21(11); p. R251-R290
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