diff --git a/src/libraries/System.Private.CoreLib/src/System/Number.BigInteger.cs b/src/libraries/System.Private.CoreLib/src/System/Number.BigInteger.cs
index c0b45828edfbb7..c19e7d036b04b3 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Number.BigInteger.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Number.BigInteger.cs
@@ -602,6 +602,11 @@ public static void DivRem(ref BigInteger lhs, ref BigInteger rhs, out BigInteger
                         {
                             remLength--;
                         }
+                        else
+                        {
+                            // As soon as we find a non-zero block, the rest of remainder is significant
+                            break;
+                        }
                     }
 
                     rem._length = remLength;