Mephenoxalone

Mephenoxalone
Clinical data
Trade names	Dorsiflex, Moderamin, Control-OM
AHFS/Drugs.com	International Drug Names
ATC code	N05BX01 (WHO) ;
Legal status
Legal status	BR: Class C1 (Other controlled substances);
Identifiers
	IUPAC name 5-[(2-methoxyphenoxy)methyl]-1,3-oxazolidin-2-one;
CAS Number	70-07-5 ;
PubChem CID	6257;
ChemSpider	6021 ;
UNII	CZ87T54W8W;
KEGG	D07318 ;
ChEMBL	ChEMBL2104790 ;
CompTox Dashboard (EPA)	DTXSID9023255 ;
ECHA InfoCard	100.000.658
Chemical and physical data
Formula	C11H13NO4
Molar mass	223.228 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2OC(COc1c(OC)cccc1)CN2;
	InChI InChI=1S/C11H13NO4/c1-14-9-4-2-3-5-10(9)15-7-8-6-12-11(13)16-8/h2-5,8H,6-7H2,1H3,(H,12,13) ; Key:ZMNSRFNUONFLSP-UHFFFAOYSA-N ;
	(what is this?) (verify)

The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.

Mephenoxalone (trade names Dorsiflex, Moderamin, Control-OM) is a muscle relaxant^[2] and mild anxiolytic.^[3] It inhibits neuron transmission, relaxing skeletal muscles by inhibiting the reflex arc.^{[citation needed]} As the effect of muscle relaxation, mephenoxalone affects mental condition, and is also a treatment for nervousness and anxiety.

References

^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^ Magnenat M (December 1961). "[The utilization in psychotherapy of a tensiolytic agent with muscle relaxant effect, Control OM (mephenoxalone), alone or associated with thymoleptics]". Therapeutische Umschau. Revue Therapeutique. 18: 516–20. PMID 14468333.
^ MIMS: Mephenoxalone

This drug article relating to the musculoskeletal system is a stub. You can help Wikipedia by expanding it.

This sedative-related article is a stub. You can help Wikipedia by expanding it.

[1] Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

[2] Magnenat M (December 1961). "[The utilization in psychotherapy of a tensiolytic agent with muscle relaxant effect, Control OM (mephenoxalone), alone or associated with thymoleptics]". Therapeutische Umschau. Revue Therapeutique. 18: 516–20. PMID 14468333.

[3] MIMS: Mephenoxalone

[1]

[2]

[3]

v t e Anxiolytics (N05B)
5-HT_1ARTooltip 5-HT1A receptor agonists	Buspirone Gepirone Tandospirone
GABA_ARTooltip GABAA receptor PAMsTooltip positive allosteric modulators	Benzodiazepines: Adinazolam Alprazolam Bromazepam Camazepam Chlordiazepoxide Clobazam Clonazepam Clorazepate Clotiazepam Cloxazolam Diazepam^# Ethyl loflazepate Etizolam Fludiazepam Halazepam Ketazolam Lorazepam^# Medazepam Nordazepam Oxazepam Pinazepam Prazepam; Others: Alpidem^‡ Barbiturates (e.g., phenobarbital) Carbamates (e.g., meprobamate) Carisoprodol Chlormezanone^‡ Ethanol (alcohol) Etifoxine
Hypnotics	Zopiclone
Gabapentinoids (α₂δ VDCC blockers)	Gabapentin Gabapentin enacarbil Phenibut Pregabalin
Antidepressants	SSRIsTooltip Selective serotonin reuptake inhibitors (e.g., escitalopram) SNRIsTooltip Serotonin-norepinephrine reuptake inhibitors (e.g., duloxetine) SARIsTooltip Serotonin antagonist and reuptake inhibitors (e.g., trazodone) TCAsTooltip Tricyclic antidepressants (e.g., clomipramine^#) TeCAsTooltip Tetracyclic antidepressants (e.g., mirtazapine) MAOIsTooltip Monoamine oxidase inhibitors (e.g., phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine
Antipsychotics	Quetiapine Flupentixol
Sympatholytics (Antiadrenergics)	Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists (e.g., clonidine, dexmedetomidine, guanfacine) Beta blockers (e.g., propranolol)
Others	Benzoctamine Cycloserine Fabomotizole Hydroxyzine Lorpiprazole Mebicar Mepiprazole Nicotine Opipramol Oxaflozane^‡ Phenaglycodol Phenibut Picamilon Selank Tiagabine Tofisopam Validolum
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

See also

References