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Tyloxapol

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This is an old revision of this page, as edited by 92.198.37.130 (talk) at 16:14, 3 March 2015 (Pharmaceutical products containing Tyloxapol and their purpose were added.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Tyloxapol
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.209.660 Edit this at Wikidata
Chemical and physical data
Formula(C15H21O(C2H4O)m)n
Molar massvariable
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Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent[citation needed] (containing mucus and pus) bronchopulmonary secretions,[1][2] administered by inhalation through a nebulizer[3] or with a stream of oxygen.

With intraperitoneal injection, tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins. This mechanism is used to induce experimental hyperlipidemia in animals.[4]

Tyloxapol is the main active ingredient of the agent Tacholiquin. Tacholiquin is an Expectorant designated for inhaling and instillation into the airways. Other brand names of pharmaceutical products containing Tyloxpol are Exosurf, Alevaire.

References

  1. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 8151722, please use {{cite journal}} with |pmid=8151722 instead.
  2. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 1555424, please use {{cite journal}} with |pmid=1555424 instead.
  3. ^ Drugs.com: Tyloxapol definition
  4. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 12231215, please use {{cite journal}} with |pmid=12231215 instead.