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Richard Laurence Millington Synge

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Richard Laurence Millington Synge
Born(1914-10-28)28 October 1914
Died18 August 1994(1994-08-18) (aged 79)
Alma materWinchester College
Trinity College, Cambridge
Known forchromatography
AwardsNobel Prize in Chemistry (1952)
John Price Wetherill Medal (1959)
Scientific career
Fieldsbiochemist

Richard Laurence Millington Synge FRS[1] (Liverpool, 28 October 1914 - Norwich, 18 August 1994) was a British biochemist, and shared the 1952 Nobel Prize in Chemistry for the invention of partition chromatography with Archer Martin.

He was a close friend of John H. Humphrey. Educated at Winchester and Trinity College, Cambridge, he spent his entire career in research, at locations including Wool Industries Research Association, Leeds (1941–1943), Lister Institute for Preventive Medicine, London (1943–1948), Rowett Research Institute, Aberdeen (1948–1967), and Food Research Institute, Norwich (1967–1976).

It was during his time in Leeds that he worked with Archer Martin, developing partition chromatography, a technique used in the separation mixtures of similar chemicals, that revolutionized analytical chemistry. Between 1942 and 1948 he studied peptides of the protein group gramicidin, work later used by Frederick Sanger in determining the structure of insulin. In March 1950 he was elected a Fellow of the Royal Society for which his candidature citation read: " Distinguished as a biochemist. Was the first to show the possibility of using counter-current liquid-liquid extraction in the separation of N-acetylamino acids. In collaboration with A.J.P. Martin this led to the development of partition chromatography, which they have applied with conspicuous success in problems related to the composition and structure of proteins, particularly wool keratin. Synge's recent work on the composition and structure of gramicidins is outstanding and illustrates vividly the great advances in technique for which he and Martin are responsible.[2]

He was for several years the treasurer of the Chemical Information Group of the Royal Society of Chemistry, and held a Professorship in Biological Sciences at the University of East Anglia from 1968–1984.

References

  1. ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1098/rsbm.1996.0028, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with |doi=10.1098/rsbm.1996.0028 instead.
  2. ^ "Library and Archive catalogue". Royal Society. Retrieved 24 October 2010.

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