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'''Tyloxapol''' is a nonionic liquid [[polymer]] of the alkyl aryl polyether alcohol type. It is used as a [[surfactant]] to aid [[liquefaction]] and removal of mucopurulent{{fact|date=December 2013}} (containing [[mucus]] and [[pus]]) bronchopulmonary secretions,<ref>{{pmid|8151722}}</ref><ref>{{pmid|1555424}}</ref> administered by inhalation through a [[nebulizer]]<ref>Drugs.com: [http://www.drugs.com/dict/tyloxapol.html Tyloxapol definition]</ref> or with a stream of oxygen.
'''Tyloxapol''' is a nonionic liquid [[polymer]] of the alkyl aryl polyether alcohol type. It is used as a [[surfactant]] to aid [[liquefaction]] and removal of mucopurulent{{fact|date=December 2013}} (containing [[mucus]] and [[pus]]) bronchopulmonary secretions,<ref>{{cite pmid|8151722}}</ref><ref>{{cite pmid|1555424}}</ref> administered by inhalation through a [[nebulizer]]<ref>Drugs.com: [http://www.drugs.com/dict/tyloxapol.html Tyloxapol definition]</ref> or with a stream of oxygen.


With [[intraperitoneal injection]], tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of [[triglyceride]]-rich [[lipoprotein]]s. This mechanism is used to induce experimental [[hyperlipidemia]] in animals.<ref>{{pmid|12231215}}</ref>
With [[intraperitoneal injection]], tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of [[triglyceride]]-rich [[lipoprotein]]s. This mechanism is used to induce experimental [[hyperlipidemia]] in animals.<ref>{{cite pmid|12231215}}</ref>


==References==
==References==

Revision as of 22:23, 12 July 2014

Tyloxapol
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.209.660 Edit this at Wikidata
Chemical and physical data
Formula(C15H21O(C2H4O)m)n
Molar massvariable
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Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent[citation needed] (containing mucus and pus) bronchopulmonary secretions,[1][2] administered by inhalation through a nebulizer[3] or with a stream of oxygen.

With intraperitoneal injection, tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins. This mechanism is used to induce experimental hyperlipidemia in animals.[4]

References

  1. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 8151722, please use {{cite journal}} with |pmid=8151722 instead.
  2. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 1555424, please use {{cite journal}} with |pmid=1555424 instead.
  3. ^ Drugs.com: Tyloxapol definition
  4. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 12231215, please use {{cite journal}} with |pmid=12231215 instead.