Idrocilamide: Difference between revisions
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'''Idrocilamide''' (trade names '''Talval''', '''Srilane''', '''Relaxnova''', '''Brolitène'''<ref name="Drugs.com">Drugs.com: {{Drugs.com|international|idrocilamide}}</ref><ref>Drugfuture.com: [http://www.drugfuture.com/chemdata/Idrocilamide.html Idrocilamide]</ref>) is a [[medication]] with skeletal muscle relaxant<ref>{{pmid|2085796}}</ref> and anti-inflammatory actions<ref name=pmid8012322>{{cite journal |author=Bannwarth B, Le Huec JC, Vinçon G, ''et al.'' |title=[Tissue and systemic diffusion of idrocilamide after cutaneous administration] |language=French |journal=Rev Rhum Ed Fr |volume=60 |issue=12 |pages=932–6 |year=1993 |month=December |pmid=8012322 |doi= |url=}}</ref> used as a topical cream to treat [[lumbago]] and other kinds of [[myalgia|muscular pain]];<ref>{{pmid|2140002}}</ref> it is available on prescription or over-the-counter{{fact|date=June 2012}} in France and various other countries.<ref name="Drugs.com" /> |
'''Idrocilamide''' (trade names '''Talval''', '''Srilane''', '''Relaxnova''', '''Brolitène'''<ref name="Drugs.com">Drugs.com: {{Drugs.com|international|idrocilamide}}</ref><ref>Drugfuture.com: [http://www.drugfuture.com/chemdata/Idrocilamide.html Idrocilamide]</ref>) is a [[medication]] with skeletal muscle relaxant<ref>{{pmid|2085796}}</ref> and anti-inflammatory actions<ref name=pmid8012322>{{cite journal |author=Bannwarth B, Le Huec JC, Vinçon G, ''et al.'' |title=[Tissue and systemic diffusion of idrocilamide after cutaneous administration] |language=French |journal=Rev Rhum Ed Fr |volume=60 |issue=12 |pages=932–6 |year=1993 |month=December |pmid=8012322 |doi= |url=}}</ref> used as a topical cream to treat [[lumbago]] and other kinds of [[myalgia|muscular pain]];<ref>{{pmid|2140002}}</ref> it is available on prescription or over-the-counter{{fact|date=June 2012}} in France and various other countries.<ref name="Drugs.com" /> |
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==Interactions== |
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Idrocilamide has been reported to be a potent inhibitor of the metabolism of caffeine.<ref name=pmid10976659>{{cite journal |author=Carrillo JA, Benitez J |title=Clinically significant pharmacokinetic interactions between dietary caffeine and medications |journal=Clin Pharmacokinet |volume=39 |issue=2 |pages=127–53 |year=2000 |month=August |pmid=10976659 |doi= |url=}}</ref><ref name=pmid7371698>{{cite journal |author=Brazier JL, Descotes J, Lery N, Ollagnier M, Evreux JC |title=Inhibition by idrocilamide of the disposition of caffeine |journal=Eur. J. Clin. Pharmacol. |volume=17 |issue=1 |pages=37–43 |year=1980 |month=January |pmid=7371698 |doi= |url=}}</ref> |
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==References== |
==References== |
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Revision as of 06:50, 4 September 2012
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| Clinical data | |
|---|---|
| Trade names | Talval, Srilane, Relaxnova, Brolitène |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Topical |
| ATC code | |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.027.414 |
| Chemical and physical data | |
| Formula | C11H13NO2 |
| Molar mass | 191.226 g/mol g·mol−1 |
| 3D model (JSmol) | |
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  (what is this?) (verify) | |
Idrocilamide (trade names Talval, Srilane, Relaxnova, Brolitène[1][2]) is a medication with skeletal muscle relaxant[3] and anti-inflammatory actions[4] used as a topical cream to treat lumbago and other kinds of muscular pain;[5] it is available on prescription or over-the-counter[citation needed] in France and various other countries.[1]
Interactions
Idrocilamide has been reported to be a potent inhibitor of the metabolism of caffeine.[6][7]
References
- ^ a b Drugs.com: International Drug Names
- ^ Drugfuture.com: Idrocilamide
- ^ PMID 2085796
- ^ Bannwarth B, Le Huec JC, Vinçon G; et al. (1993). "[Tissue and systemic diffusion of idrocilamide after cutaneous administration]". Rev Rhum Ed Fr (in French). 60 (12): 932–6. PMID 8012322.
{{cite journal}}: Explicit use of et al. in:|author=(help); Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ PMID 2140002
- ^ Carrillo JA, Benitez J (2000). "Clinically significant pharmacokinetic interactions between dietary caffeine and medications". Clin Pharmacokinet. 39 (2): 127–53. PMID 10976659.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Brazier JL, Descotes J, Lery N, Ollagnier M, Evreux JC (1980). "Inhibition by idrocilamide of the disposition of caffeine". Eur. J. Clin. Pharmacol. 17 (1): 37–43. PMID 7371698.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link)
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