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==Interactions==
==Interactions==
ACVR2A has been shown to [[Protein-protein_interaction|interact]] with [[INHBA]], [[SYNJ2BP]] and [[ACVR1B]].<ref name=pmid10746731>{{cite journal | quotes = yes |last=Lewis |first=K A |authorlink= |coauthors=Gray P C, Blount A L, MacConell L A, Wiater E, Bilezikjian L M, Vale W |year=[[2000]]|month=Mar. |title=Betaglycan binds inhibin and can mediate functional antagonism of activin signalling |journal=[[Nature (journal)|Nature]] |volume=404 |issue=6776 |pages=411-4 |publisher= |location = [[ENGLAND]]| issn = 0028-0836| pmid = 10746731 |doi = 10.1038/35006129 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid9202237>{{cite journal | quotes = yes |last=Martens |first=J W |authorlink= |coauthors=de Winter J P, Timmerman M A, McLuskey A, van Schaik R H, Themmen A P, de Jong F H |year=[[1997]]|month=Jul. |title=Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells |journal=[[Endocrinology (journal)|Endocrinology]] |volume=138 |issue=7 |pages=2928-36 |publisher= |location = [[UNITED STATES]]| issn = 0013-7227| pmid = 9202237 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid15451561>{{cite journal | quotes = yes |last=Tsuchida |first=Kunihiro |authorlink= |coauthors=Nakatani Masashi, Matsuzaki Takashi, Yamakawa Norio, Liu ZhongHui, Bao YongLi, Arai Koji Y, Murakami Tatsuya, Takehara Yuka, Kurisaki Akira, Sugino Hiromu |year=[[2004]]|month=Oct. |title=Novel factors in regulation of activin signaling |journal=[[Mol. Cell. Endocrinol.]] |volume=225 |issue=1-2 |pages=1-8 |publisher= |location = [[Ireland]]| issn = 0303-7207| pmid = 15451561 |doi = 10.1016/j.mce.2004.02.006 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid11882656>{{cite journal | quotes = yes |last=Matsuzaki |first=Takashi |authorlink= |coauthors=Hanai Sayuri, Kishi Hisashi, Liu ZhongHui, Bao YongLi, Kikuchi Akira, Tsuchida Kunihiro, Sugino Hiromu |year=[[2002]]|month=May. |title=Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway |journal=[[J. Biol. Chem.]] |volume=277 |issue=21 |pages=19008-18 |publisher= |location = [[United States]]| issn = 0021-9258| pmid = 11882656 |doi = 10.1074/jbc.M112472200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid9892009>{{cite journal | quotes = yes |last=Lebrun |first=J J |authorlink= |coauthors=Takabe K, Chen Y, Vale W |year=[[1999]]|month=Jan. |title=Roles of pathway-specific and inhibitory Smads in activin receptor signaling |journal=[[Mol. Endocrinol.]] |volume=13 |issue=1 |pages=15-23 |publisher= |location = [[UNITED STATES]]| issn = 0888-8809| pmid = 9892009 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid8612709>{{cite journal | quotes = yes |last=De Winter |first=J P |authorlink= |coauthors=De Vries C J, Van Achterberg T A, Ameerun R F, Feijen A, Sugino H, De Waele P, Huylebroeck D, Verschueren K, Van Den Eijden-Van Raaij A J |year=[[1996]]|month=May. |title=Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I. receptors |journal=[[Exp. Cell Res.]] |volume=224 |issue=2 |pages=323-34 |publisher= |location = [[UNITED STATES]]| issn = 0014-4827| pmid = 8612709 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
ACVR2A has been shown to [[Protein-protein_interaction|interact]] with [[INHBA]],<ref name=pmid10746731>{{cite journal | quotes = yes |last=Lewis |first=K A |authorlink= |coauthors=Gray P C, Blount A L, MacConell L A, Wiater E, Bilezikjian L M, Vale W |year=[[2000]]|month=Mar. |title=Betaglycan binds inhibin and can mediate functional antagonism of activin signalling |journal=[[Nature (journal)|Nature]] |volume=404 |issue=6776 |pages=411-4 |publisher= |location = ENGLAND| issn = 0028-0836| pmid = 10746731 |doi = 10.1038/35006129 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid9202237>{{cite journal | quotes = yes |last=Martens |first=J W |authorlink= |coauthors=de Winter J P, Timmerman M A, McLuskey A, van Schaik R H, Themmen A P, de Jong F H |year=[[1997]]|month=Jul. |title=Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells |journal=[[Endocrinology (journal)|Endocrinology]] |volume=138 |issue=7 |pages=2928-36 |publisher= |location = UNITED STATES| issn = 0013-7227| pmid = 9202237 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[SYNJ2BP]]<ref name=pmid15451561>{{cite journal | quotes = yes |last=Tsuchida |first=Kunihiro |authorlink= |coauthors=Nakatani Masashi, Matsuzaki Takashi, Yamakawa Norio, Liu ZhongHui, Bao YongLi, Arai Koji Y, Murakami Tatsuya, Takehara Yuka, Kurisaki Akira, Sugino Hiromu |year=[[2004]]|month=Oct. |title=Novel factors in regulation of activin signaling |journal=Mol. Cell. Endocrinol. |volume=225 |issue=1-2 |pages=1-8 |publisher= |location = Ireland| issn = 0303-7207| pmid = 15451561 |doi = 10.1016/j.mce.2004.02.006 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid11882656>{{cite journal | quotes = yes |last=Matsuzaki |first=Takashi |authorlink= |coauthors=Hanai Sayuri, Kishi Hisashi, Liu ZhongHui, Bao YongLi, Kikuchi Akira, Tsuchida Kunihiro, Sugino Hiromu |year=[[2002]]|month=May. |title=Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway |journal=J. Biol. Chem. |volume=277 |issue=21 |pages=19008-18 |publisher= |location = United States| issn = 0021-9258| pmid = 11882656 |doi = 10.1074/jbc.M112472200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[ACVR1B]].<ref name=pmid9892009>{{cite journal | quotes = yes |last=Lebrun |first=J J |authorlink= |coauthors=Takabe K, Chen Y, Vale W |year=[[1999]]|month=Jan. |title=Roles of pathway-specific and inhibitory Smads in activin receptor signaling |journal=Mol. Endocrinol. |volume=13 |issue=1 |pages=15-23 |publisher= |location = UNITED STATES| issn = 0888-8809| pmid = 9892009 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid8612709>{{cite journal | quotes = yes |last=De Winter |first=J P |authorlink= |coauthors=De Vries C J, Van Achterberg T A, Ameerun R F, Feijen A, Sugino H, De Waele P, Huylebroeck D, Verschueren K, Van Den Eijden-Van Raaij A J |year=[[1996]]|month=May. |title=Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I. receptors |journal=Exp. Cell Res. |volume=224 |issue=2 |pages=323-34 |publisher= |location = UNITED STATES| issn = 0014-4827| pmid = 8612709 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>

==References==
==References==
{{reflist}}
{{reflist}}

Revision as of 11:44, 23 July 2009

Template:PBB

Activin A receptor, type IIA, also known as ACVR2A, is a human gene.[1] ACVR2A is an activin type 2 receptor. Template:PBB Summary

Interactions

ACVR2A has been shown to interact with INHBA,[2][3] SYNJ2BP[4][5] and ACVR1B.[6][7]

References

  1. ^ "Entrez Gene: ACVR2A activin A receptor, type IIA".
  2. ^ Lewis, K A (2000). "Betaglycan binds inhibin and can mediate functional antagonism of activin signalling". Nature. 404 (6776). ENGLAND: 411–4. doi:10.1038/35006129. ISSN 0028-0836. PMID 10746731. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help); Unknown parameter |quotes= ignored (help)CS1 maint: year (link)
  3. ^ Martens, J W (1997). "Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells". Endocrinology. 138 (7). UNITED STATES: 2928–36. ISSN 0013-7227. PMID 9202237. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help); Unknown parameter |quotes= ignored (help)CS1 maint: year (link)
  4. ^ Tsuchida, Kunihiro (2004). "Novel factors in regulation of activin signaling". Mol. Cell. Endocrinol. 225 (1–2). Ireland: 1–8. doi:10.1016/j.mce.2004.02.006. ISSN 0303-7207. PMID 15451561. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help); Unknown parameter |quotes= ignored (help)CS1 maint: year (link)
  5. ^ Matsuzaki, Takashi (2002). "Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway". J. Biol. Chem. 277 (21). United States: 19008–18. doi:10.1074/jbc.M112472200. ISSN 0021-9258. PMID 11882656. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help); Unknown parameter |quotes= ignored (help)CS1 maint: unflagged free DOI (link) CS1 maint: year (link)
  6. ^ Lebrun, J J (1999). "Roles of pathway-specific and inhibitory Smads in activin receptor signaling". Mol. Endocrinol. 13 (1). UNITED STATES: 15–23. ISSN 0888-8809. PMID 9892009. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help); Unknown parameter |quotes= ignored (help)CS1 maint: year (link)
  7. ^ De Winter, J P (1996). "Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I. receptors". Exp. Cell Res. 224 (2). UNITED STATES: 323–34. ISSN 0014-4827. PMID 8612709. {{cite journal}}: Check date values in: |year= (help); Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help); Unknown parameter |quotes= ignored (help)CS1 maint: year (link)

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