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#REDIRECT[[Effects of cannabis]]
{{Infobox disease
| Name = Cannabis withdrawal
| Image = Tetrahydrocannabinol.svg
| Caption = [[Tetrahydrocannabinol|THC]]
| DiseasesDB =
| ICD10 = {{ICD10|F|12||f|10}}.3
| ICD9 = {{ICD9|292.0}}
| ICDO =
| OMIM =
| MedlinePlus =
| eMedicineSubj =
| eMedicineTopic =
| MeshID =
}}
'''Cannabis withdrawal''' is a form of [[withdrawal]] associated with the substance [[cannabis]]. It is included in the proposed revision of [[DSM-5]].<ref name="urlProposed Revision | APA DSM-5">{{cite web |url=http://www.dsm5.org/ProposedRevisions/Pages/proposedrevision.aspx?rid=430# |title=Proposed Revision &#124; APA DSM-5 |format= |work= |accessdate=2010-04-26}}</ref>

At one time cannabis was considered a drug that had no withdrawal symptoms because users did not display symptoms similar to those withdrawing from [[alcohol withdrawal|alcohol]] or [[opiate withdrawal|opiates]]. Contrary to this, recent experimental research points to cessasion of symptoms assotiated with marijuana use when they cease said marijuana use. To quote directly "Current users experienced significant increases in anxiety, irritability, physical tension, and physical symptoms and decreases in mood and appetite during marijuana withdrawal. These symptoms were most pronounced during the initial 10 days of abstinence, but some were present for the entire 28-day withdrawal period. These findings support the notion of a marijuana withdrawal syndrome in humans." While the results of this study do show an effect of stopping marijuana, the symptoms decreased appetite, increased tension and irritability are the opposite effects seen of marijuana use. Naturally, it must be proven concretely "withdrawal" symptoms are actual due to a physiological response from lack of marijuana, not the natural state the body was in prior to marijuana use.

Kouri and Pope examined withdrawal symptoms over 28 days abstinence from cannabis,<ref name="pmid11127420">{{cite pmid|11127420}}</ref> while Budney et al. looked at a time period of abstinence of 45 days.<ref name="Hughes, J.R. 2003">{{cite pmid|12943018}}</ref> Their study assessed withdrawal symptoms among chronic cannabis users who were assessed daily on various symptoms while on a hospital ward for 28 days. They rated mood, anxiety, depression and irritability and compared them to those of two control groups of abstinent former heavy cannabis users and non-users of cannabis. Chronic cannabis users showed decreases in mood and appetite and increases in irritability and anxiety and their scores on the [[Hamilton Rating Scale for Depression]] scale increased. Both studies used urinalysis to ensure abstinence, and showed that withdrawal symptoms began within 1–3 days of abstinence and lasted for 10–14 days.<ref name="Budney, A.J. 2001">{{cite pmid|11576029}}</ref><ref name="Hughes, J.R. 2003"/><ref name="pmid11127420"/> According to Budney et al., the withdrawal syndrome associated with cannabis use is similar to that for [[tobacco]] but of lesser magnitude than withdrawal from other drugs like opiates or alcohol. <ref name="Hughes, J.R. 2003"/>

Significantly, evidence indicates that withdrawal symptoms are alleviated when cannabis users resume using cannabis after a period of abstinence,<ref name="Budney, A.J. 2001"/> and recent laboratory research has focused on the role of brain chemistry in cannabis dependence.

==See also==
* [[Long-term effects of cannabis]]

==References==
{{Reflist|2}}

==External links==
* [http://www.marijuana-anonymous.org/literature/pamphlets/detoxing-from-marijuana Detoxing from Marijuana, by Marijuana Anonymous]
* [http://drugwarfacts.org/cms/?q=node/28 Addictive Properties of Popular Drugs, from Common Sense for Drug Policy]

{{Psychoactive substance use}}
{{Cannabis}}

[[Category:Cannabis]]
[[Category:Withdrawal syndromes]]

[[fa:نشانه‌های ترک ماری‌جوانا]]
[[fi:Kannabisvieroitusoireyhtymä]]

Latest revision as of 06:42, 7 February 2013