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{{Infobox Anatomy
{{Infobox anatomy
| Name = Germinal epithelium (female)
| Name = Germinal epithelium (female)
| Latin =
| Latin =
| Image = Gray1163.png
| GraySubject =
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| Caption = Section of the ovary. 1. '''Germinal epithelium'''. 2. Central stroma. 3. Peripheral stroma. 4. Bloodvessels. 5. Vesicular follicles in their earliest stage. 6, 7, 8. More advanced follicles. 9. An almost mature follicle. 9'. Follicle from which the ovum has escaped. 10. Corpus luteum.
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| GrayPage =
| Image = Ovaire 1.JPG
| Image2 = File:Histology of ovarian surface epithelium.jpg
| Caption2 = Histology of ovarian surface epithelium. H&E stain. The epithelium is the chain-like covering with round dark blue nuclei at top.
| Caption = Diagram in French. "Epithelium ovarien" labeled at upper right.
| Image2 = Gray1163.png
| Precursor =
⚫
| System =
⚫
| Caption2 = Section of the ovary. 1. '''Germinal epithelium'''. 2. Central stroma. 3. Peripheral stroma. 4. Bloodvessels. 5. Vesicular follicles in their earliest stage. 6, 7, 8. More advanced follicles. 9. An almost mature follicle. 9'. Follicle from which the ovum has escaped. 10. Corpus luteum.
| Precursor =
| Artery =
| System =
| Vein =
| Artery =
| Nerve =
| Vein =
| Lymph =
⚫
}}
| Nerve =
{{Epithelia series}}
| Lymph =
The '''ovarian surface epithelium''', also called the '''germinal epithelium''' of Waldeyer,<ref>{{cite journal |author=Nishida T, Nishida N |title=Reinstatement of "germinal epithelium" of the ovary |journal=Reprod Biol Endocrinol |volume=4 |pages=42 |year=2006 |pmid=16923182 |pmc=1560142 |doi=10.1186/1477-7827-4-42 |doi-access=free }}</ref> or coelomic epithelium, is a layer of simple [[Squamous epithelial cell|squamous]]-to-[[cuboidal epithelial cell]]s covering the [[ovary]].<ref>{{Cite journal | last1 = Auersperg | first1 = N. | last2 = Wong | first2 = A. S. | last3 = Choi | first3 = K. C. | last4 = Kang | first4 = S. K. | last5 = Leung | first5 = P. C. | title = Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology | journal = Endocrine Reviews | volume = 22 | issue = 2 | pages = 255–288 | year = 2001 | doi = 10.1210/edrv.22.2.0422 | pmid = 11294827| s2cid = 11013148 | doi-access = free }}</ref>
| MeshName =
| MeshNumber =
| DorlandsPre = e_13
| DorlandsSuf = 12339107
⚫
|}}
The surface of the [[ovary]] is covered by a layer of [[Simple cuboidal epithelium|simple cuboidal cells]] which constitutes the '''germinal epithelium''' of Waldeyer.<ref>{{cite journal |author=Nishida T, Nishida N |title=Reinstatement of "germinal epithelium" of the ovary |journal=Reprod Biol Endocrinol. |volume=4 |issue= |pages=42 |year=2006 |pmid=16923182 |pmc=1560142 |doi=10.1186/1477-7827-4-42 }}</ref>


The term ''germinal epithelium'' is a misnomer as it does not give rise to primary follicles.<ref name="ross">{{cite book | title=Histology: A Text and Atlas | publisher=Lippincott Williams & Wilkins | author=Ross M, Pawlina W | year=2011 | isbn=978-0-7817-7200-6 | page=832 | edition=6th}}</ref>
⚫
These cells are derived from the [[mesoderm]] during embryonic development and are closely related to the [[mesothelium]] of the [[peritoneum]]. The germinal epithelium gives the ovary a dull gray color as compared with the shining smoothness of the [[peritoneum]]; and the transition between the [[mesothelium]] of the peritoneum and the columnar cells which cover the ovary is usually marked by a line around the anterior border of the ovary.


==Composition==
The germinal epithelium gives rise to [[Folliculogenesis#Primary|primary follicles]] and is the main origin of [[tumors]] in the ovaries.
⚫
These cells are derived from the [[mesoderm]] during embryonic development and are closely related to the [[mesothelium]] of the [[peritoneum]]. The germinal epithelium gives the ovary a dull gray color as compared with the shining smoothness of the [[peritoneum]]; and the transition between the [[mesothelium]] of the peritoneum and the cuboidal cells which cover the ovary is usually marked by a line around the anterior border of the ovary.

==Diseases==
Ovarian surface epithelium can give rise to [[surface epithelial-stromal tumor]].


==References==
==References==
⚫
{{Gray's}}
{{reflist}}
{{reflist}}


==External links==
==External links==
*{{BUHistology|18403loa}}
*{{BUHistology|18403loa}}
*{{OklahomaHistology|83_07}}
*{{OklahomaHistology|83_07}}

⚫
{{Gray's}}


{{Female reproductive system}}
{{Female reproductive system}}

{{Portal bar|Anatomy}}


{{DEFAULTSORT:Germinal Epithelium (Female)}}
{{DEFAULTSORT:Germinal Epithelium (Female)}}
[[Category:Female reproductive system]]
[[Category:Mammal female reproductive system]]


{{genitourinary-stub}}

[[cs:Zárodečný epitel]]
[[it:Epitelio germinale]]
[[sk:Zárodočný epitel]]

Latest revision as of 19:51, 14 June 2024

Germinal epithelium (female)
Section of the ovary. 1. Germinal epithelium. 2. Central stroma. 3. Peripheral stroma. 4. Bloodvessels. 5. Vesicular follicles in their earliest stage. 6, 7, 8. More advanced follicles. 9. An almost mature follicle. 9'. Follicle from which the ovum has escaped. 10. Corpus luteum.
Histology of ovarian surface epithelium. H&E stain. The epithelium is the chain-like covering with round dark blue nuclei at top.
Identifiers
FMA18629
Anatomical terminology
This article is part of a series on
Epithelia
Squamous epithelial cell
Columnar epithelial cell
Cuboidal epithelial cell
Specialised epithelia
Other

The ovarian surface epithelium, also called the germinal epithelium of Waldeyer,[1] or coelomic epithelium, is a layer of simple squamous-to-cuboidal epithelial cells covering the ovary.[2]

The term germinal epithelium is a misnomer as it does not give rise to primary follicles.[3]

Composition

[edit]

These cells are derived from the mesoderm during embryonic development and are closely related to the mesothelium of the peritoneum. The germinal epithelium gives the ovary a dull gray color as compared with the shining smoothness of the peritoneum; and the transition between the mesothelium of the peritoneum and the cuboidal cells which cover the ovary is usually marked by a line around the anterior border of the ovary.

Diseases

[edit]

Ovarian surface epithelium can give rise to surface epithelial-stromal tumor.

References

[edit]

Public domain This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

  1. ^ Nishida T, Nishida N (2006). "Reinstatement of "germinal epithelium" of the ovary". Reprod Biol Endocrinol. 4: 42. doi:10.1186/1477-7827-4-42. PMC 1560142. PMID 16923182.
  2. ^ Auersperg, N.; Wong, A. S.; Choi, K. C.; Kang, S. K.; Leung, P. C. (2001). "Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology". Endocrine Reviews. 22 (2): 255–288. doi:10.1210/edrv.22.2.0422. PMID 11294827. S2CID 11013148.
  3. ^ Ross M, Pawlina W (2011). Histology: A Text and Atlas (6th ed.). Lippincott Williams & Wilkins. p. 832. ISBN 978-0-7817-7200-6.
[edit]
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