Iron supplement: Difference between revisions

Iron can be supplemented [[oral route|by mouth]] using various forms, such as [[iron(II) sulfate]]. This is the most common and well studied soluble iron [[salt]] sold under brand names such as Feratab, Fer-Iron, and Slow-FE. It is in complex with [[gluconate]], [[dextran]], [[carbonyl iron]], and other salts. [[Ascorbic acid]], vitamin C, increases the absorption of non-heme sources of iron.<ref>{{cite journal | vauthors = Lynch SR, Cook JD | title = Interaction of vitamin C and iron | journal = Annals of the New York Academy of Sciences | volume = 355 | issue = 1 | pages = 32–44 | year = 1980 | pmid = 6940487 | doi = 10.1111/j.1749-6632.1980.tb21325.x | s2cid = 35848195 | citeseerx = 10.1.1.530.1906 | bibcode = 1980NYASA.355...32L }}</ref>

 

 

Another alternative is ferrous [[glycine]] [[sulfate]] or ferroglycine sulfate, has less gastrointestinal side-effects than standard preparations such as iron fumarate.<ref>{{cite journal | vauthors = Aronstam A, Aston DL | title = A comparative trial of a controlled-release iron tablet preparation ('Ferrocontin' Continus) and ferrous fumarate tablets | journal = Pharmatherapeutica | volume = 3 | issue = 4 | pages = 263–267 | year = 1982 | pmid = 7146040 }}</ref> {{Better source needed|date=January 2020}} It is unusual among oral preparations of iron supplements in that the iron in this preparation has very high oral bioavailability, especially in the liquid formulation. This option should be evaluated before resorting to parenteral therapy. It is especially useful in iron deficiency anemia associated with [[autoimmune gastritis]] and ''[[Helicobacter pylori]]'' gastritis, where it generally has satisfactory effect.<ref>{{cite journal | vauthors = Hershko C, Ianculovich M, Souroujon M | title = Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis | journal = Acta Haematologica | volume = 118 | issue = 1 | pages = 19–26 | year = 2007 | pmid = 17426393 | doi = 10.1159/000101701 | s2cid = 46720321 }}</ref>