Iltovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as natural hosts. There are only two species in this genus. Diseases associated with this genus include: acute respiratory diseases: gaHV-1: infectious laryngotracheitis; psHV-1: Pacheco's disease.[1][2]

Iltovirus
Transmission electron micrograph of Gallid alphaherpesvirus 1 virions
Virus classification Edit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Orthoherpesviridae
Subfamily: Alphaherpesvirinae
Genus: Iltovirus
Species

See text

Species

edit

The genus consists of the following two species:[2]

Structure

edit

Viruses in Iltovirus are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 120-200 nm. Genomes are linear and non-segmented, around 150kb in length.[1]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Iltovirus Spherical pleomorphic T=16 Enveloped Linear Monopartite

Life cycle

edit

Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral gB, gC, gD and gH proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as the natural host. Transmission routes are contact, contamination, and air borne particles.[1]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Iltovirus Birds: galliform: psittacine None Cell receptor endocytosis Budding Nucleus Nucleus Oral-fecal; aerosol

References

edit
  1. ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 10 May 2021.
edit