Meptazinol (trade name Meptid) is an opioid analgesic for use with moderate to severe pain, most commonly used to treat pain in obstetrics (childbirth). A partial µ-opioid receptor agonist, its mixed agonist/antagonist activity affords it a lower risk of dependence and abuse than full µ agonists like morphine. Meptazinol exhibits not only a short onset of action, but also a shorter duration of action relative to other opioids such as morphine, pentazocine, or buprenorphine.[1]
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| AHFS/Drugs.com | International Drug Names |
| Dependence liability | Low |
| Routes of administration | Oral, IM, IV |
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| Metabolism | The peak analgesic effect is seen within 30–60 minutes and lasts about 3–4 hours. |
| Elimination half-life | Half-Life (1.4–4 hours). |
| Excretion | The drug is rapidly metabolised to the glucuronide, and mostly excreted in the urine. |
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| ECHA InfoCard | 100.053.718 |
| Chemical and physical data | |
| Formula | C15H23NO |
| Molar mass | 233.34922 g/mol g·mol−1 |
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References
- ^ Holmes B, Ward A. "Meptazinol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy." Drugs. 1985 Oct; 30(4):285-312. PMID 2998723
External links
- Meptazinol at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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