Posterior pituitary: Difference between revisions

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A few sources include the [[pars intermedia]] as part of the posterior lobe, but this is a minority view. It is based upon the gross anatomical separation of the posterior and anterior pituitary along the cystic remnants of Rathke's pouch, causing the pars intermedia to remain attached to the neurohypophysis.
 
==Function==
 
===Hormone secretion===
Two hormones are classically considered as being related to the posterior pituitary: oxytocin and vasopressin. These hormones are created in the hypothalamus and released in the posterior pituitary. After creation, they are stored in neurosecretory vesicles regrouped into Herring bodies before being secreted in the posterior pituitary via the bloodstream.
 
{| class="wikitable"
! Hormone
! Other names
! Symbol(s)
! Main targets
! Effect
! Source
|-
| [[Oxytocin]]
|
| OT
| [[Uterus]], [[mammary gland]]s
| [[Uterine contraction]]s; [[lactation]]
| [[supraoptic nucleus|supraoptic]] and [[paraventricular nucleus|paraventricular nuclei]]
|-
| [[Vasopressin]]
| Antidiuretic hormone
| VP, AVP, ADH
| [[Kidney]]s and [[arteriole]]s
| Stimulates water retention; raises blood pressure by contracting arterioles
| [[supraoptic nucleus|supraoptic]] and [[paraventricular nucleus|paraventricular nuclei]]
|}
 
==Clinical significance==