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Since 2016 the Mayo Clinic, Rochester, has been ranked as the #1 overall hospital in the [[United States]] by [[U.S. News & World Report]]. Almost 5,000 hospitals were considered and ranked in 16 specialties, from cancer and heart disease to respiratory disorders and urology; 153 (just over 3 percent of the total) were ranked in at least one of the 16 specialties. Of the 153 hospitals ranked in one or more specialties, 20 qualified for the Honor Roll, earning high scores in at least six specialties. Mayo Clinic, Rochester, was ranked in the top 10 in all but one of 16 specialties, in the top 4 in 13 specialties, and was the #1 ranked hospital in 8 of the 12 data-driven specialties. This year U.S. News expanded its common procedures and conditions list to 9 individual measures. Mayo was one of fewer than 70 hospitals to score High Performing in every category.<ref name="Browning">{{cite news|url=http://health.usnews.com/best-hospitals/area/mn/mayo-clinic-6610451|title=US News / Healthcare / Best Hospitals / Mayo Clinic|date=August 3, 2016|access-date=August 3, 2016}}</ref> Additionally, Mayo was the only hospital on the 2016–2017 honor roll also to receive 5 stars from CMS.<ref>{{Cite web|url=http://www.beckershospitalreview.com/quality/how-did-cms-rate-us-news-20-honor-roll-hospitals.html|title=How did CMS rate US News' 20 Honor Roll hospitals?|last=Punke|first=Heather|website=beckershospitalreview.com|access-date=August 3, 2016}}</ref> Every Mayo Clinic hospital received an "A" safety rating from Leapfrog in its April 2017 report.<ref>{{Cite web| url=http://www.healthcarefinancenews.com/news/see-which-hospitals-earned-leapfrog|title=See which hospitals earned an 'A' from Leapfrog|website=Healthcare Finance News|language=en|access-date=May 15, 2017}}</ref>
In 2021–22, Mayo Clinic, Rochester, was ranked again as the #1 overall hospital in the [[United States]] by [[U.S. News & World Report]].
 
In 2023, May Clinic was ranked the number four health care institution in the world<ref>{{Cite web |title=2023 tables: Institutions - healthcare {{!}} Annual tables {{!}} Nature Index |url=https://www.nature.com/nature-index/annual-tables/2023/institution/healthcare/all/global |access-date=2024-02-27 |website=www.nature.com}}</ref> based on its research output in the [[Nature Index]].
 
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