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{{Use dmy dates|date=October 2016}}
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▲| caption = Rectal bulb syringe to administer smaller enemas
An '''enema''', also known as a '''clyster''', is an injection of fluid into the [[Large intestine|lower bowel]] by way of the [[rectum]].<ref name=Cullingworth_introduction>Cullingworth, ''A Manual of Nursing, Medical and Surgical'':155</ref> The word enema can also refer to the liquid injected,<ref name=Merriam-Webster_Enema>{{cite web |url=https://www.merriam-webster.com/dictionary/enema |title=enema noun |work=[[Webster's Dictionary#Noah Webster's American Dictionary of the English Language|Noah Webster's American Dictionary of the English Language]] |publisher=[[Merriam-Webster]] |access-date=2019-04-15 }}</ref><ref name=Free_Dictionary_Enema>{{cite web |url=https://www.thefreedictionary.com/Enema |title=Enema|work=The Free Dictionary |publisher=[[TheFreeDictionary.com]] |access-date=2019-04-15 }}</ref> as well as to a device for administering such an injection.<ref>{{cite web |url=https://www.dictionary.com/browse/enema |title=enema |work=[[Dictionary.com]] |publisher=s[[Ask.com]] |access-date=2019-04-15 }}</ref>
In standard medicine, the most frequent uses of enemas are to relieve constipation and for bowel cleansing before a medical examination or procedure;<ref name= Biology_Online_Dictionary>{{cite web |url = http://www.biology-online.org/dictionary/Soapsuds_enema |title = Soapsuds enema |website = Biology-Online Dictionary |publisher = Biology-Online |access-date = 6 August 2014 }}</ref> also, they are employed as a [[lower gastrointestinal series]] (also called a barium enema),<ref name=NIH_barium>{{
== Medical usage ==
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''In alphabetical order''
* [[Peanut oil|Arachis oil (peanut oil)]] enema is useful for softening stools which are impacted higher than the rectum.<ref name="NHS_Laxativives">{{cite web |url=http://www.nhsgrampian.org/nhsgrampian/GJF_general_new.jsp;jsessionid=9D853EB1A4631954DC26F785F611F2B1?pContentID=4659&p_applic=CCC&pElementID=522&pMenuID=7&p_service=Content.show& |title=NHS Grampian Medicines Management – Laxatives |date=2011 |work=NHS Grampian Campaign |publisher=National Health Service |access-date=4 March 2019 }}{{Dead link|date=July 2023 |bot=InternetArchiveBot |fix-attempted=yes }}</ref>
* [[Bisacodyl]] stimulates [[enteric nervous system|enteric nerves]] to cause colonic contractions.<ref>{{cite book |doi=10.1002/14356007.a15_183 |chapter=Laxatives |title=Ullmann's Encyclopedia of Industrial Chemistry |year=2000 |last1=Engelhorn |first1=Robert |last2=Seeger |first2=Ernst |last3=Zwaving |first3=Jan H. |isbn=3527306730 }}</ref><ref>{{cite web |url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=324e61eb-8f6b-48d7-85c2-b1b5642691c9 |title=Label: FLEET- bisacodyl enema |access-date=3 March 2019}}</ref>▼
* [[Dantron]] is a stimulant drug and stool softener<ref>{{cite book |doi=10.1016/B978-1-4377-1015-1.00018-7 |chapter=Constipation during active cancer therapy |title=Supportive Oncology |year=2011 |last1=Sykes |first1=Nigel P. |pages=177–186 |isbn=9781437710151 }}</ref> used alone or in combinations in enemas.<ref>{{cite web |url=https://www.whocc.no/atc_ddd_index/?code=A06AG&showdescription=yes |title=A06AG Enemas |date=13 December 2018 |work=WHO Collaborating Centre for Drug Statistics Methodology |publisher=World Health Organization |access-date=3 March 2019}}</ref> Considered to be a [[carcinogen]]<ref>{{cite web |url=https://ntp.niehs.nih.gov/pubhealth/roc/listings/index.html?substance=Danthron |title=Report on Carcinogens, Fourteenth Edition |date=November 2016 |work=Report on Carcinogens |publisher=National Toxicology Program, Department of Health and Human Services (HHS) |access-date=3 March 2019}}</ref> its use is limited, e.g., restricted in the [[United Kingdom|UK]] to patients who already have a diagnosis of terminal cancer and not used at all in the [[United States|USA]].▼
▲[[Bisacodyl]] stimulates [[enteric nervous system|enteric nerves]] to cause colonic contractions.<ref>{{cite book |doi=10.1002/14356007.a15_183 |chapter=Laxatives |title=Ullmann's Encyclopedia of Industrial Chemistry |year=2000 |last1=Engelhorn |first1=Robert |last2=Seeger |first2=Ernst |last3=Zwaving |first3=Jan H. |isbn=3527306730 }}</ref><ref>{{cite web |url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=324e61eb-8f6b-48d7-85c2-b1b5642691c9 |title=Label: FLEET- bisacodyl enema |access-date=3 March 2019}}</ref>
* [[Docusate#Constipation|Docusate]]<ref>{{cite web |url=https://www.nursingtimes.net/clinical-archive/medicine-management/docusate-sodium-18-12-2004/ |title=Docusate sodium|date=18 December 2004}}</ref><ref>{{Cite web |url=https://www.drugs.com/cdi/colace-microenema.html|title=Colace Microenema: Indications, Side Effects, Warnings|website=Drugs.com}}</ref>▼
* Glycerol has a hyperosmotic effect and can be used as a small-volume (2–10 ml) enema (or suppository).<ref name=
▲[[Dantron]] is a stimulant drug and stool softener<ref>{{cite book |doi=10.1016/B978-1-4377-1015-1.00018-7 |chapter=Constipation during active cancer therapy |title=Supportive Oncology |year=2011 |last1=Sykes |first1=Nigel P. |pages=177–186 |isbn=9781437710151 }}</ref> used alone or in combinations in enemas.<ref>{{cite web |url=https://www.whocc.no/atc_ddd_index/?code=A06AG&showdescription=yes |title=A06AG Enemas |date=13 December 2018 |work=WHO Collaborating Centre for Drug Statistics Methodology |publisher=World Health Organization |access-date=3 March 2019}}</ref> Considered to be a [[carcinogen]]<ref>{{cite web |url=https://ntp.niehs.nih.gov/pubhealth/roc/listings/index.html?substance=Danthron |title=Report on Carcinogens, Fourteenth Edition |date=November 2016 |work=Report on Carcinogens |publisher=National Toxicology Program, Department of Health and Human Services (HHS) |access-date=3 March 2019}}</ref> its use is limited, e.g., restricted in the [[United Kingdom|UK]] to patients who already have a diagnosis of terminal cancer and not used at all in the [[United States|USA]].
* [[Mineral oil]] is used as a lubricant because most of the ingested material is excreted in the stool rather than being absorbed by the body.<ref name="food">{{Cite web |title=206. Food-grade mineral oil (FAO Nutrition Meetings Report Series 48a) |url=https://inchem.org/documents/jecfa/jecmono/v48aje08.htm |archive-url=https://web.archive.org/web/20070806023007/http://inchem.org/documents/jecfa/jecmono/v48aje08.htm|url-status=dead|archive-date=6 August 2007 |website=inchem.org}}</ref>▼
* [[Sodium phosphates#Uses|Sodium phosphate]].<ref>{{cite web |url=https://www.drugs.com/cdi/sodium-phosphates-enema.html |title=Sodium Phosphates Enema |access-date=3 March 2019}}</ref><ref>{{cite web |url=https://medlineplus.gov/druginfo/meds/a614018.html |title=Sodium Phosphate Rectal |access-date=3 March 2019}}</ref> Also known by the brand name Fleet. Available at drugstores; usually self-administered. [[buffer solution|Buffered]] [[sodium phosphates#Use|sodium phosphate]] solution draws additional water from the bloodstream into the colon to increase the effectiveness of the enema. But it can be rather irritating to the colon, causing intense cramping or "griping."<ref>{{cite web |title=Fleet Enema Side Effects |url=https://www.drugs.com/sfx/fleet-enema-side-effects.html |website=www.drugs.com |publisher=Drugs.com |access-date=July 12, 2021}}</ref> Fleet enemas usually causes a bowel movement in 1 to 5 minutes. Known [[Sodium phosphates#Adverse effects|adverse effects]].▼
▲[[Docusate#Constipation|Docusate]]<ref>{{cite web |url=https://www.nursingtimes.net/clinical-archive/medicine-management/docusate-sodium-18-12-2004/ |title=Docusate sodium|date=18 December 2004}}</ref><ref>{{Cite web |url=https://www.drugs.com/cdi/colace-microenema.html|title=Colace Microenema: Indications, Side Effects, Warnings|website=Drugs.com}}</ref>
* [[Sorbitol#Laxative|Sorbitol]] pulls water into the large intestines causing distention, thereby stimulating the normal forward movement of the bowels. Sorbitol is found in some dried fruits and may contribute to the laxative effects of prunes.<ref>{{cite journal |last1=Stacewicz-Sapuntzakis |first1=Maria |last2=Bowen |first2=Phyllis E. |last3=Hussain |first3=Erum A. |last4=Damayanti-Wood |first4=Bernadette I. |last5=Farnsworth |first5=Norman R. |title=Chemical Composition and Potential Health Effects of Prunes: A Functional Food? |journal=Critical Reviews in Food Science and Nutrition |date=July 2001 |volume=41 |issue=4 |pages=251–286 |doi=10.1080/20014091091814 |pmid=11401245 |s2cid=31159565 }}</ref> and is available for taking orally as a laxative.<ref>{{cite web|url=http://www.cancer.org/docroot/CDG/content/CDG_sorbitol.asp |title=ACS :: Cancer Drug Guide: sorbitol |archive-url=https://web.archive.org/web/20070630001051/http://www.cancer.org/docroot/CDG/content/CDG_sorbitol.asp |archive-date=2007-06-30}}</ref><ref>{{Cite web | url=https://www.webmd.com/drugs/2/drug-10305/sorbitol/details |title = Drugs & Medications}}</ref> As an enema for constipation, the recommended adult dose is 120 mL of 25-30% solution, administered once.<ref>{{cite web |url=https://reference.medscape.com/drug/sorbitol-342033|title= Sorbitol| access-date=3 March 2019}}</ref> Note that Sorbitol is an ingredient of the MICROLAX Enema.▼
▲Glycerol has a hyperosmotic effect and can be used as a small-volume (2–10 ml) enema (or suppository).<ref name= Glycerol/>
▲[[Mineral oil]] is used as a lubricant because most of the ingested material is excreted in the stool rather than being absorbed by the body.<ref name=food>{{Cite web |title=206. Food-grade mineral oil (FAO Nutrition Meetings Report Series 48a) |url=https://inchem.org/documents/jecfa/jecmono/v48aje08.htm |archive-url=https://web.archive.org/web/20070806023007/http://inchem.org/documents/jecfa/jecmono/v48aje08.htm|url-status=dead|archive-date=6 August 2007 |website=inchem.org}}</ref>
▲[[Sodium phosphates#Uses|Sodium phosphate]].<ref>{{cite web |url=https://www.drugs.com/cdi/sodium-phosphates-enema.html |title=Sodium Phosphates Enema |access-date=3 March 2019}}</ref><ref>{{cite web |url=https://medlineplus.gov/druginfo/meds/a614018.html |title=Sodium Phosphate Rectal |access-date=3 March 2019}}</ref> Also known by the brand name Fleet. Available at drugstores; usually self-administered. [[buffer solution|Buffered]] [[sodium phosphates#Use|sodium phosphate]] solution draws additional water from the bloodstream into the colon to increase the effectiveness of the enema. But it can be rather irritating to the colon, causing intense cramping or "griping."<ref>{{cite web |title=Fleet Enema Side Effects |url=https://www.drugs.com/sfx/fleet-enema-side-effects.html |website=www.drugs.com |publisher=Drugs.com |access-date=July 12, 2021}}</ref> Fleet enemas usually causes a bowel movement in 1 to 5 minutes. Known [[Sodium phosphates#Adverse effects|adverse effects]].
▲[[Sorbitol#Laxative|Sorbitol]] pulls water into the large intestines causing distention, thereby stimulating the normal forward movement of the bowels. Sorbitol is found in some dried fruits and may contribute to the laxative effects of prunes.<ref>{{cite journal |last1=Stacewicz-Sapuntzakis |first1=Maria |last2=Bowen |first2=Phyllis E. |last3=Hussain |first3=Erum A. |last4=Damayanti-Wood |first4=Bernadette I. |last5=Farnsworth |first5=Norman R. |title=Chemical Composition and Potential Health Effects of Prunes: A Functional Food? |journal=Critical Reviews in Food Science and Nutrition |date=July 2001 |volume=41 |issue=4 |pages=251–286 |doi=10.1080/20014091091814 |pmid=11401245 |s2cid=31159565 }}</ref> and is available for taking orally as a laxative.<ref>{{cite web|url=http://www.cancer.org/docroot/CDG/content/CDG_sorbitol.asp |title=ACS :: Cancer Drug Guide: sorbitol |archive-url=https://web.archive.org/web/20070630001051/http://www.cancer.org/docroot/CDG/content/CDG_sorbitol.asp |archive-date=2007-06-30}}</ref><ref>{{Cite web | url=https://www.webmd.com/drugs/2/drug-10305/sorbitol/details |title = Drugs & Medications}}</ref> As an enema for constipation, the recommended adult dose is 120 mL of 25-30% solution, administered once.<ref>{{cite web |url=https://reference.medscape.com/drug/sorbitol-342033|title= Sorbitol| access-date=3 March 2019}}</ref> Note that Sorbitol is an ingredient of the MICROLAX Enema.
====== Compounded from multiple ingredients ======<!-- Klyx redirects to here -->
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[[Sodium citrate/sodium lauryl sulfoacetate/glycerol|MICROLAX®]] (not to be confused with Micralax) combines the action of [[sodium citrate]], a peptidising agent which can displace bound water present in the faeces, with sodium alkyl sulphoacetate, a wetting agent, and with glycerol, an anal mucosa irritant and hyperosmotic. However, also sold under the name "Micralax", is a preparation containing [[sorbitol]] rather than glycerol;<ref>{{cite web |url=https://www.nps.org.au/medical-info/medicine-finder/microlax-enema |title=Microlax Enema |date=2018 |work=NPS MedicineWise |publisher=National Prescribing Service |access-date=4 March 2019}}</ref> which was initially tested in preparation for [[sigmoidoscopy]].<ref>{{cite journal |author=W. Lieberman|year=1964|title=Rapid patient preparation for sigmoidoscopy by microenema.|journal=American Journal of Proctology|volume=15|pages=138–41|pmid=14139893}}</ref>
Micolette Micro-enema® contains 45 mg sodium lauryl sulphoacetate, 450 mg per 5 ml sodium citrate BP, and 625 mg glycerol BP<ref>{{cite web |url=https://www.medicines.org.uk/emc/product/4569/smpc |title=Micolette Micro-enema |date=10 July 2015 |work
==== Chronic treatments ====
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An international consensus on when and how to use transanal irrigation for people with bowel problems was published in 2013, offering practitioners a clear, comprehensive and simple guide to practice for the emerging therapeutic area of transanal irrigation.<ref name="Consensus review 2013" />
The term ''retrograde irrigation'' distinguishes this procedure from the [[Malone antegrade continence enema]], where irrigation fluid is introduced into the colon proximal to the anus via a surgically created irrigation port.<ref>{{Cite journal |last1=Spinelli |first1=Michele |last2=Sampogna |first2=Gianluca |last3=Rizzato |first3=Luigi |last4=Spinelli |first4=Antonella |last5=Sammartano |first5=Fabrizio |last6=Cimbanassi |first6=Stefania |last7=Montanari |first7=Emanuele |last8=Chiara |first8=Osvaldo |date=2021-04-23 |title=The Malone antegrade continence enema adapting a transanal irrigation system in patients with neurogenic bowel dysfunction |journal=Spinal Cord Series and Cases |volume=7 |issue=1 |pages=34 |doi=10.1038/s41394-021-00397-3 |issn=2058-6124 |pmc=8065210 |pmid=33893272}}</ref>
===== Bowel management =====
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[[File:Barium Contrast Enema.jpg|thumb|A barium enema in a disposable bag manufactured for that purpose]]
In a [[lower gastrointestinal series]] an enema that may contain [[Barium sulphate#Radiocontrast agent|barium sulfate]] powder or a water-soluble [[contrast agent]] is used in the [[
Failure to expel all of the barium may cause constipation or possible impaction<ref name=Hopkins_Barium>{{cite web |url=https://www.hopkinsmedicine.org/healthlibrary/test_procedures/gastroenterology/barium_enema_92,P07687 |title=aGastroenterology Tests and Procedures – Barium Enema |work=Health Library |publisher=Johns Hopkins School of Medicine |access-date=2019-04-01 }}</ref> and a patient who has no bowel movement for more than two days or is unable to pass gas rectally should promptly inform a physician and may require an enema or laxative.<ref name=SW_Med_Center>{{cite web |url=http://www.swmedcenter.com/index.php/services-2/diagnostic-imaging/bariumgastroview-enema/ |title=Barium/Gastroview Enema |work=Our Services |publisher=Southwest Medical Center in Liberal, Kansas, USA |access-date=2019-04-01 }}</ref>
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=== Inhibiting pathological defecation ===
* [[Traveller's diarrhea]]'s symptoms treated with an enema of [[sodium butyrate]], [[organic acid]]s, and A-300 [[silicon dioxide]] can be successfully decreased with lack of observed side effects.<ref name= Travellers_Diarrhea/>
* [[Shigellosis]] treatment benefits from adjunct therapy with butyrate enemas, promoting healing of the rectal mucosa and inflammation, but not helping in clinical recovery from shigellosis. Use of an 80 ml of a sodium butyrate isotonic enema administered every 12 hours has been studied and found effective.<ref>{{cite journal |title= Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial |journal = BMC Infectious Diseases|volume = 12|pages = 111|date = 10 May 2012 |publisher = U.S. Department of Health & Human Services, National Institutes of Health (NIH) |pmc = 3447723|last1 = Raqib|first1 = R.|last2 = Sarker|first2 = P.|last3 = Mily|first3 = A.|last4 = Alam|first4 = N. H.|last5 = Arifuzzaman|first5 = A. S.|last6 = Rekha|first6 = R. S.|last7 = Andersson|first7 = J.|last8 = Gudmundsson|first8 = G. H.|last9 = Cravioto|first9 = A.|last10 = Agerberth|first10 = B.|pmid = 22574737|doi = 10.1186/1471-2334-12-111 | doi-access=free }}</ref>
=== Other ===
* There have been a few cases in remote or rural settings, where rectal fluids have been used to rehydrate a person. Benefits include not needing to use sterile fluids.<ref name="pmid19856644">{{cite journal |last1=Tremayne |first1=Vincent |title=Proctoclysis: emergency rectal fluid infusion |journal=Nursing Standard |date=23 September 2009 |volume=24 |issue=3 |pages=46–48 |doi=10.7748/ns2009.09.24.3.46.c7271 |pmid=19856644 }}</ref>
* Introducing healthy bacterial flora through infusion of stool, known as a [[fecal microbiota transplant]], was first performed in 1958 employing retention enemas. Enemas remained the most common method until 1989, when alternative means of administration were developed.<ref>{{cite journal |last1=Bakken |first1=Johan S. |last2=Borody |first2=Thomas |last3=Brandt |first3=Lawrence J. |last4=Brill |first4=Joel V. |last5=Demarco |first5=Daniel C. |last6=Franzos |first6=Marc Alaric |last7=Kelly |first7=Colleen |last8=Khoruts |first8=Alexander |last9=Louie |first9=Thomas |last10=Martinelli |first10=Lawrence P. |last11=Moore |first11=Thomas A. |last12=Russell |first12=George |last13=Surawicz |first13=Christina |author14=Fecal Microbiota Transplantation Workgroup |title=Treating Clostridium difficile Infection With Fecal Microbiota Transplantation |journal=Clinical Gastroenterology and Hepatology |date=December 2011 |volume=9 |issue=12 |pages=1044–1049 |doi=10.1016/j.cgh.2011.08.014 |pmid=21871249 |pmc=3223289 }}</ref> As of 2013, [[colonoscope]] implantation has been preferred over fecal enemas because by using the former method, the entire colon and ileum can be inoculated, but enemas reach only to the [[splenic flexure]].<ref>{{cite journal |title=Fecal microbiota transplantation: past, present and future |issue=1 |pages=79–84 |author=Olga C. Aroniadis |author2=Lawrence J. Brandt |date=January 2013 |journal=Current Opinion in Gastroenterology |volume=29 |publisher=[[Lippincott Williams & Wilkins]] |doi=10.1097/MOG.0b013e32835a4b3e |pmid=23041678 |s2cid=39943619 |doi-access=free }}</ref>
* A patient unable to be fed otherwise can be [[nutrition|nourished]] by an [[enteral administration]] of predigested foods, which is known as a [[nutrient enema]].<ref>{{cite web |url=https://medical-dictionary.thefreedictionary.com/nutrient+enema |title=nutrient enema |work=The Free Dictionary |publisher=[[TheFreeDictionary.com]] |access-date=2019-05-01 }}</ref> This treatment is ancient, dating back at least to the second century CE when documented by [[Galen]],<ref name=Galen/> and commonly used in the Middle Ages,<ref name="pmid20766702">{{cite journal |vauthors=Short AR, Bywaters HW |title=Amino-Acids and Sugars in Rectal Feeding |journal=Br Med J |volume=1 |issue=2739 |pages=1361–1367 |date=June 1913 |pmid=20766702 |pmc=2299894 |doi=10.1136/bmj.1.2739.1361 |jstor=25302025}}</ref> remaining a common technique in 19th century,<ref>{{cite journal |vauthors=Mackenzie JW |title=The nutrient enema |journal=Arch. Dis. Child. |volume=18 |issue=93 |pages=22–27 |date=March 1943 |pmid=21032242 |pmc=1987791 |doi=10.1136/adc.18.93.22}}</ref> and as recently as 1941 the [[United States Department of War|U. S. military]]'s manual for hospital diets prescribes their use.<ref>{{cite web |url=https://collections.nlm.nih.gov/ext/dw/33320860R/PDF/33320860R.pdf |title=War Department Technical Manual Hospital Diets |date=October 13, 1941 |work=Technical Manuals |publisher=[[United States Department of War]] |access-date=2019-05-01 }}</ref> Nutrient enemas have been superseded in modern medical care by [[tube feeding]] and [[Parenteral nutrition|intravenous feeding]].{{Citation needed|reason=|date=May 2019}}
* Enemas have been used around the time of childbirth; however, there is no evidence for this practice and it is now discouraged.<ref name=Enemas_during_labour>{{cite web |url = https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0010611/ |title = Enemas during labour |date = 4 July 2013 |website = Cochrane Database of Systematic Reviews: Plain Language Summaries |publisher = National Institutes of Health (NIH) |access-date = 14 June 2016 }}</ref>
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== Adverse effects ==
Improper administration of an enema can cause electrolyte imbalance (with repeated enemas) or ruptures to the bowel or rectal tissues which can be unnoticed as the rectum is insensitive to pain,<ref name=enemapain>{{cite journal |last1=Lee |first1=Seokyoun |last2=Kwon |first2=Jungnam |last3=Lee |first3=Junhee |title=Rectal perforations caused by cleansing enemas in chronically constipated patients: Two case reports |journal=SAGE Open Medical Case Reports |date=8 July 2020 |volume=8 |pages=2050313X20938251 |doi=10.1177/2050313X20938251 |pmid=32685153 |pmc=7346698 }}</ref> resulting in internal [[bleeding]]. However, these occurrences are rare in healthy, [[sobriety|sober]] adults. Internal bleeding or rupture may leave the individual exposed to infections from intestinal bacteria. Blood resulting from tears in the colon may not always be visible, but can be distinguished if the feces are unusually dark or have a red hue. If intestinal rupture is suspected, medical assistance should be obtained immediately.<ref name=Nursing_and_Allied_Health>{{Cite encyclopedia |title=Enema administration |encyclopedia=Encyclopedia of Nursing and Allied Health |first=Mary Elizabeth |last=Martelli |url=http://findarticles.com/p/articles/mi_gGENH/is_/ai_2699003276.htm |access-date=11 January 2008 |via=[[FindArticles]] |url-status=dead |archive-date=23 January 2008 |archive-url=https://web.archive.org/web/20080123073414/http://findarticles.com/p/articles/mi_gGENH/is_/ai_2699003276.htm}}</ref> Frequent use of enemas can cause laxative dependency.<ref>{{Cite web |url=https://www.webmd.com/drugs/2/drug-14831/fleet-enema-rectal/details |title=Fleet Enema Rectal: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing |website=WebMD}}</ref>
The enema tube and solution may stimulate the [[vagus nerve]], which may trigger an [[Heart arrhythmia|arrhythmia]] such as [[bradycardia]].
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[[File:Afrikanische Holzplastik.jpg|thumb|Pressure enema from an animal bladder (African wooden sculpture, 19th century)]]
In parts of Africa the [[calabash]] gourd is used traditionally to administer enemas. On the Ivory Coast the narrow neck of the gourd filled with water is inserted the patient's rectum and the contents are then injected by means of an attendant's forcible oral inflation, or, alternatively, a patient may self-administer the enema by using suction to create a negative pressure in the gourd, placing a finger at the opening, and then upon anal insertion, removing the finger to allow atmospheric pressure to effect the flow. In South Africa, [[Bhaca]] people used an ox horn to administer enemas.<ref>Annals of the South African Museum, page 18</ref> Along the upper Congo River an enema apparatus is made by making a hole in one end of the gourd for filling it, and using a resin to attach a hollow cane to the gourd's neck. The cane is inserted into the anus of the patient who is in a posture that allows gravity to effect infusion of the fluid.<ref>Friedenwald & Morrison, 'Part I:75-76</ref>
==== Americas ====
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The [[Olmec]] from their middle preclassic period (10th through 7th centuries BCE) through the Spanish Conquest used trance-inducing substances ceremonially, and these were ingested via, among other routes, enemas administered using jars.
As further described below in [[
For combating illness and discomfort of the digestive tract, the Mayan also employed enemas, as documented during the colonial period, e.g., in the [[Florentine Codex]].<ref name=Hallucinogenic_pre-Columbian/>
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In 1694 [[François Mauriceau]] in his early-modern treatise, ''The Diseases of Women with Child,'' records that both midwives and man-midwives commonly administered clysters to labouring mothers just prior to their delivery.<ref>{{cite journal |doi=10.1136/adc.66.1_Spec_No.78 |title=Francois Mauriceau (1637-1709) and maternal posture for parturition |year=1991 |last1=Dunn |first1=P. M. |journal=Archives of Disease in Childhood |volume=66 |issue=1 Spec No |pages=78–79 |pmid=1996901 |pmc=1590357 }}</ref>
Clysters were administered for symptoms of constipation and, with more questionable effectiveness, stomach aches and other illnesses.{{when|date=July 2020}}{{Citation needed|date=July 2020}}<ref>{{Cite
[[File:A monkey rejects the old style clyster for his new 'clyso-pompe', which he fills with opium and marshmallow Wellcome V0011775.jpg|thumb|19th century satirical cartoon of a monkey rejecting an old style clyster for a new design, filled with marshmallow and opium]]
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In the 18th century Europeans began emulating the [[indigenous peoples of the Americas#North America|indigenous peoples of North America's]] use of tobacco smoke enemas to resuscitate drowned people.<ref name=BCMJ>{{cite web |url=https://www.bcmj.org/special-feature/special-feature-tobacco-smoke-enemas |title=Special feature: Tobacco smoke enemas |author=Sterling Haynes |date=December 2012 |work=British Columbia Medical Journal |publisher=Doctors of BC |access-date=2019-03-29 }}</ref> Tobacco resuscitation kits consisting of a pair of bellows and a tube were provided by the Royal Humane Society of London and placed at various points along the Thames.<ref name=Royal_Pharmaceutical /> Furthermore, these enemas came to be employed for headaches, respiratory failure, colds, hernias, abdominal cramps, typhoid fever, and cholera outbreaks.<ref name=BCMJ/>
Clysters were a favourite medical treatment in the [[bourgeoisie]] and [[nobility]] of the Western world up to the 19th century. As medical knowledge was fairly limited at the time, purgative clysters were used for a wide variety of [[ailment]]s, the foremost of which were [[stomach ache]]s and constipation.<ref name="Pharmacological treatment">{{cite journal |last1=Clemens |first1=Katri E. |last2=Faust |first2=Markus |last3=Jaspers |first3=Birgit |last4=Mikus |first4=Gerd |title=Pharmacological treatment of constipation in palliative care |journal=Current Opinion in Supportive
According to [[Louis de Rouvroy, duc de Saint-Simon|the duc de Saint-Simon]], clysters were so popular at the court of King [[Louis XIV of France]] that [[Marie Adélaïde of Savoy|the duchess of Burgundy]] had her servant give her a clyster in front of the King (her modesty being preserved by an adequate posture) before going to the [[comedy]]. However, he also mentions the astonishment of the King and Mme de Maintenon that she should take it before them.<ref>Saint-Simon, ''Memoires'', vol. 10, [http://rouvroy.medusis.com/docs/1004.html ch. 4].</ref>
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In the 19th century many new types of enema administration equipment were devised. Devices allowing gravity to infuse the solution, like those mentioned above used by South American indigenous people and like the enema bag described by Johann Jacob Woyts, came into common use. These consist of a nozzle at the end of a hose which connects a reservoir, either a bucket or a rubber bag, which is filled with liquid and held or hung above the recipient.<ref name=Royal_Pharmaceutical />
In the early 20th century the disposable [[
== Society and culture ==
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===== Colonic irrigation =====
The term "colonic irrigation" is commonly used in [[gastroenterology]] to refer to the practice of introducing water through a colostomy or a surgically constructed conduit as a treatment for constipation.<ref name="pmid11113099">{{cite journal |last1=Locke |first1=G.Richard |last2=Pemberton |first2=John H. |last3=Phillips |first3=Sidney F. |title=AGA technical review on constipation |journal=Gastroenterology |date=December 2000 |volume=119 |issue=6 |pages=1766–1778 |doi=10.1053/gast.2000.20392 |pmid=11113099 |doi-access=free }}</ref> The [[Food and Drug Administration]] has ruled that colonic irrigation equipment is not approved for sale for the purpose of general well-being<ref>{{cite web |title = Subpart F—Therapeutic Devices Sec. 876.5220 Colonic irrigation system |website = Code of Federal Regulations, Title 21 Food and Drugs, Subchapter H – Medical Devices, Part 876 –
===== Colon cleansing =====
{{Main|Colon cleansing}}
The same term is also used in [[alternative medicine]] where it may involve the use of substances mixed with water in order to [[Detoxification (alternative medicine)|detoxify]] the body. Practitioners believe the accumulation of fecal matter in the large intestine leads to ill health.<ref name="pmid11124189">{{cite journal |author = Whorton J |title = Civilisation and the colon: constipation as the "disease of diseases" |journal = BMJ |volume = 321 |issue = 7276 |pages = 1586–9 |year = 2000 |pmid = 11124189 |pmc = 1119264 |doi = 10.1136/bmj.321.7276.1586 }}</ref> This resurrects the old medical concept of ''autointoxication'' which was orthodox doctrine up to the end of the 19th century but which has now been discredited.<ref name=Ernst>{{cite journal |last1=Ernst |first1=E. |title=Colonic Irrigation and the Theory of Autointoxication: A Triumph of Ignorance over Science |journal=Journal of Clinical Gastroenterology |date=June 1997 |volume=24 |issue=4 |pages=196–198 |doi=10.1097/00004836-199706000-00002 |pmid=9252839 |doi-access=free }}</ref><ref>{{cite journal |author = Kaiser |title = The Case Against Colonic Irrigation |journal = California Morbidity |issue = 38 |year = 1985 }}</ref><ref name = Chen>{{cite journal |vauthors = Chen TS, Chen PS |title = Intestinal autointoxication: a medical leitmotif |journal = Journal of Clinical Gastroenterology |volume = 11 |issue = 4 |pages = 434–41 |year = 1989 |pmid = 2668399 |doi = 10.1097/00004836-198908000-00017 }}</ref>
=====Kellogg's enemas=====
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Both women and men may enjoy sexual enema play, heterosexually and homosexually, experiencing [[sexual arousal]] from enemas which they find gratifying or sensual<ref name="Agnew, 1982">Agnew, 1982</ref><ref name="Denko"/> and which can be an auxiliary to, or even a substitute for, genital [[Human sexual activity|sexual activity]].<ref name="Agnew, 1982"/><ref name="Denko">{{cite journal|last=Denko|first=JD.|date=April 1976|title=Amplification of the erotic enema deviance|journal=Am J Psychother|volume=30|pages=236–55 | issue=2|pmid=937588|doi=10.1176/appi.psychotherapy.1976.30.2.236}}</ref>
Klismaphiles may perceive pleasure from a large, water
That some women use enemas while masturbating was documented by [[Alfred Kinsey]] in ''Sexual Behavior in the Human Female'': "There were still other masturbatory techniques which were regularly or occasionally employed by some 11 percent of the females in the sample... Douches, streams of running water, vibrators, urethral insertions, enemas, other anal insertions, sado-masochistic activity, and still other methods were occasionally employed, but none of them in any appreciable number of cases."<ref>{{Citation | last1 = Kinsey | first1 = Alfred Charles | title = Sexual Behavior in the Human Female | publisher = Indiana University Press | place = Bloomington, Indiana, U.S.A. | year = 1953 | isbn = 978-0-253-33411-4 }}</ref>
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===== BDSM =====
[[File:5000 ml Enema Bag with Dildo Nozzle Filled Hanging in Tree.jpg|thumb|right|upright
Enemas are sometimes used in [[sadomasochism|sadomasochistic]] activities<ref>Brame et al., ''Different loving – The World of Sexual Dominance and Submission'':513,516</ref><ref>Agnew, 2000:74,77,78,79</ref> for [[erotic humiliation]]<ref>Brame et al., ''Different loving – The World of Sexual Dominance and Submission'':515,516,520</ref> or for physical discomfort.<ref>Brame et al., ''Different loving – The World of Sexual Dominance and Submission'':513,517</ref>
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===== Rectal douching =====
{{Main|Rectal douching}}
Another sexual use for enemas is to empty the rectum as a prelude to other anal sexual activities such as [[anal sex
This is different from klismaphilia, in which the enema is enjoyed for itself and as a part of sexual arousal and gratification.<ref name="Agnew, 2000:76"/>
Rectal douching is a common practice among people who take a receptive role in anal sex<ref name="JavanbakhtStahlman2014">{{cite journal |last1=Javanbakht |first1=Marjan |last2=Stahlman |first2=Shauna |last3=Pickett |first3=Jim |last4=LeBlanc |first4=Marc-André |last5=Gorbach |first5=Pamina M |title=Prevalence and types of rectal douches used for anal intercourse: results from an international survey |journal=BMC Infectious Diseases |date=December 2014 |volume=14 |issue=1 |pages=95 |doi=10.1186/1471-2334-14-95 |pmid=24555695 |pmc=4015843 |doi-access=free }}</ref> although rectal douching before anal sex may increase the risk of transferring [[HIV]],<ref name="Carballo-DiéguezBauermeister2007">{{cite journal|last1=Carballo-Diéguez|first1=Alex|last2=Bauermeister|first2=José A.|last3=Ventuneac|first3=Ana|last4=Dolezal|first4=Curtis|last5=Balan|first5=Ivan|last6=Remien|first6=Robert H.|title=The Use of Rectal Douches among HIV-uninfected and Infected Men who Have Unprotected Receptive Anal Intercourse: Implications for Rectal Microbicides|journal=AIDS and Behavior|volume=12|issue=6|year=2007|pages=860–866|issn=1090-7165|doi=10.1007/s10461-007-9301-0|pmid=17705033|pmc=2953367}}</ref> [[hepatitis B]],<ref name="SchreederThompson1982">{{cite journal|last1=Schreeder|first1=M. T.|last2=Thompson|first2=S. E.|last3=Hadler|first3=S. C.|last4=Berquist|first4=K. R.|last5=Zaidi|first5=A.|last6=Maynard|first6=J. E.|last7=Ostrow|first7=D.|last8=Judson|first8=F. N.|last9=Braff|first9=E. H.|last10=Nylund|first10=T.|last11=Moore|first11=J. N.|last12=Gardner|first12=P.|last13=Doto|first13=I. L.|last14=Reynolds|first14=G.|title=Hepatitis B in Homosexual Men: Prevalence of Infection and Factors Related to Transmission|journal=Journal of Infectious Diseases|volume=146|issue=1|year=1982|pages=7–15|issn=0022-1899|doi=10.1093/infdis/146.1.7|pmid=7086206}}</ref> and other diseases.<ref>{{cite journal |title=Lymphogranuloma venereum proctitis in men who have sex with men is associated with anal enema use and high-risk behavior |last1=de Vries |first1=Henry J.C. |last2=van der Bij |first2=Akke K. |last3=Fennema |first3=Johan S.A. |last4=Smit |first4=Colette |last5=de Wolf |first5=Frank |last6=Prins |first6=Maria | last7=Coutinho | first7=Roel A. | last8=MorrÉ | first8=Servaas|journal=Sexually Transmitted Diseases |date=2008 |volume=35 |issue=2 |pages=203–208 |doi=10.1097/OLQ.0b013e31815abb08 |pmid=18091565 |s2cid=2065170 |url=https://dare.uva.nl/personal/pure/en/publications/lymphogranuloma-venereum-proctitis-in-men-who-have-sex-with-men-is-associated-with-anal-enema-use-and-highrisk-behavior(6b9b21d8-9369-4f55-a0e5-c6804db29083).html |doi-access=free }}</ref>
==== Intoxication ====
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Enemas have also been forcibly applied as a means of punishment.
In the [[Guantanamo Bay detention camp#Torture|Guantanamo Bay Detention Camp]], the [[Senate Intelligence Committee report on CIA torture]] documented instances of enemas being used by the [[Central Intelligence Agency]] in order to ensure "total control" over detainees.<ref>{{cite news|last1=Rushe|first1=Dominic|last2=MacAskill|first2=Ewen|last3=Cobain|first3=Ian|last4=Yuhas|first4=Alan|last5=Laughland|first5=Oliver|title=Rectal rehydration and waterboarding: the CIA torture report's grisliest findings|url=https://www.theguardian.com/us-news/2014/dec/09/cia-torture-report-worst-findings-waterboard-rectal|access-date=13 March 2015|agency=[[The Guardian]]|date=9 December 2014}}</ref> Enemas, officials said, are uncomfortable and degrading,<ref>{{cite web|url=https://www.nytimes.com/2005/01/01/us/fresh-details-emerge-on-harsh-methods-at-guantanamo.html|title=Fresh Details Emerge on Harsh Methods at Guantánamo|author=Neil A. Lewis|date=2005-01-01|department=Archives – 2005|work=[[The New York Times]]|access-date=2019-04-20}}</ref> The CIA forced nutrient enema on detainees who attempted hunger strikes, documenting "With head lower than torso … sloshing up the large intestines … [what] I infer is that you get a tube up as you can … We used the largest Ewal {{sic}} tube we had" wrote an officer,<ref>{{cite web|url=https://www.theguardian.com/us-news/2014/dec/09/cia-report-rectal-feeding-detainees|title=Controversial 'rectal feeding' technique used to control detainees' behaviour|date=9 December 2014|work=[[The Guardian]]|access-date=2019-04-20}}</ref> and "violent enemas" is how a detainee described what he received.<ref>{{cite web|url=https://www.nytimes.com/2015/06/06/opinion/a-detainee-describes-more-cia-torture.html|title=A Detainee Describes More C.I.A. Torture|author=The Editorial Board |date=2015-06-05|department=Editorial|work=[[The New York Times]]|access-date=2019-04-22}}</ref>
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In the [[Theatre of Dionysus|Dionysus]]' [[satyr play]] ''Limos'', [[Silenus]] attempts to give an enema to [[Heracles]].<ref>{{cite book|last=Shaw|first=Carl A.|date=2014|title=Satyric Play: The Evolution of Greek Comedy and Satyr Drama|page=15|location=Oxford, England|publisher=Oxford University Press|isbn=978-0-19-995094-2}}</ref>
In [[Miguel de Cervantes|Cervantes]]' ''[[Don Quixote]]'', a narrative to Sancho includes “The Knight of the Sun ... bound hand and foot ... was administered a clyster of snow water and sand that almost disracted him"<ref>Friedenwald & Morrison, Part I:99</ref>▼
▲In [[Miguel de Cervantes|Cervantes]]' [[Don Quixote]], a narrative to Sancho includes “The Knight of the Sun ... bound hand and foot ... was administered a clyster of snow water and sand that almost disracted him"<ref>Friedenwald & Morrison, Part I:99</ref>
In the 17th century, satirists made physicians a favorite target, resembling [[Molière]]'s caricature whose prescription for anything was "clyster, bleed, purge," or "purge, bleed, clyster".<ref>Magner, ''A History of Medicine'':218</ref>
In Molière's play ''[[The Imaginary Invalid]]'', Argan, a severe [[hypochondriac]], is addicted to enemas as indicated by such lines as when Bĕralde asks, "Can't you be one moment without a purge?"<ref>{{cite web|url=https://the-mercurian.com/2018/05/10/moliere-at-versailles/|title=?Molière at Versailles|author=Molière|date=2018-05-10|work=Theater in Translation|publisher=The Mercurian|access-date=2020-07-18}}</ref>
In [[Grace Metalious]]'s novel [[Peyton Place (novel)|''Peyton Place'']], the town doctor tells of "a young boy with the worst case of dehydration I ever saw. It came from getting too many enemas that he didn't need. Sex, with a capital S-E-X.".<ref>{{cite web|url=https://www.nytimes.com/2014/03/09/books/review/whats-it-like-reading-peyton-place-today.html|title=What's It Like Reading 'Peyton Place' Today?|author=Thomas Mallon |author2=Anna Holmes |date=2014-03-04|department=Book Review|work=The New York Times|access-date=2019-04-18}}</ref> As a teenager, the boy enjoys receiving enemas from his mother.<ref>{{cite web|url=https://exlibrisregina.com/2016/09/20/my-return-to-peyton-place/|title=My Return to Peyton Place|author=R. Saint Claire|date=2016-09-20|work=Ex Libris Regina|publisher=R. Saint Claire|access-date=2019-04-18|archive-url=https://web.archive.org/web/20190219184420/https://exlibrisregina.com/2016/09/20/my-return-to-peyton-place/|archive-date=February 19, 2019|url-status=dead}}</ref>▼
In [[Flora Rheta Schreiber]]'s book [[Sybil (Schreiber book)|''Sybil'']], Sybil's psychiatrist asks her "What's Mama been doing to you, dear?...I know she gave you the enemas."<ref>{{cite web |url=https://www.nytimes.com/2011/10/16/magazine/a-girl-not-named-sybil.html|title=A Girl Not Named Sybil |author=Debbie Nathan|date=2011-10-14|work=[[The New York Times Magazine]]|access-date=2019-04-21}}</ref>▼
▲In [[Grace Metalious]]'s novel [[Peyton Place (novel)|Peyton Place]], the town doctor tells of "a young boy with the worst case of dehydration I ever saw. It came from getting too many enemas that he didn't need. Sex, with a capital S-E-X.".<ref>{{cite web|url=https://www.nytimes.com/2014/03/09/books/review/whats-it-like-reading-peyton-place-today.html|title=What's It Like Reading 'Peyton Place' Today?|author=Thomas Mallon |author2=Anna Holmes |date=2014-03-04|department=Book Review|work=The New York Times|access-date=2019-04-18}}</ref> As a teenager, the boy enjoys receiving enemas from his mother.<ref>{{cite web|url=https://exlibrisregina.com/2016/09/20/my-return-to-peyton-place/|title=My Return to Peyton Place|author=R. Saint Claire|date=2016-09-20|work=Ex Libris Regina|publisher=R. Saint Claire|access-date=2019-04-18|archive-url=https://web.archive.org/web/20190219184420/https://exlibrisregina.com/2016/09/20/my-return-to-peyton-place/|archive-date=February 19, 2019|url-status=dead}}</ref>
▲In [[Flora Rheta Schreiber]]'s book [[Sybil (Schreiber book)|Sybil]], Sybil's psychiatrist asks her "What's Mama been doing to you, dear?...I know she gave you the enemas."<ref>{{cite web |url=https://www.nytimes.com/2011/10/16/magazine/a-girl-not-named-sybil.html|title=A Girl Not Named Sybil |author=Debbie Nathan|date=2011-10-14|work=[[The New York Times Magazine]]|access-date=2019-04-21}}</ref>
==== Film ====
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In ''[[The Right Stuff (film)|The Right Stuff]]'', during flight training astronaut [[Alan Shepard]] retains a barium enema,<ref>{{cite web|url=https://www.nytimes.com/1983/10/21/movies/film-right-stuff-on-astronauts.html|title='Right Stuff,' on astronauts|author=Vincent Canby|date=1983-10-21|department=Film|work=The New York Times|access-date=2019-03-27}}</ref> given two floors away from a toilet, embarrassedly riding a public elevator wearing a [[hospital gown]] and holding the enema bag with its tip still inserted in him.<ref>{{cite web|url=https://teachwithmovies.org/the-right-stuff/|title=The Right Stuff|publisher=Teach with Movies|access-date=2019-03-27}}</ref><ref>{{cite web|url=https://www.imdb.com/title/tt0086197/characters/nm0001277|title=The Right Stuff|website=[[IMDb]]|access-date=2019-03-27}}</ref>
''[[Water Power (film)|Water Power]]'' is a film loosely based on the real-life exploits of [[Michael H. Kenyon]], an
==== Song ====
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== See also ==
{{Portal|Medicine}}
* [[Bowel management]]
* [[Dry enema]]
* [[Fecal microbiota transplant]]
* [[Murphy drip]]
* [[Nutrient enema]]
* [[Tobacco smoke enema]]
* [[Transanal irrigation]]
|