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Algestone acetonide: Difference between revisions

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{{Short description|Chemical compound}}
* [[{{Distinguish|Algestone acetophenide]]}}▼
{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| IUPAC_name = (1R1''R'',2S2''S'',4R4''R'',8S8''S'',9S9''S'',12S12''S'',13R13''R'')-8-acetyl-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0²<sup>2,⁹9</sup>.0⁴0<sup>4,⁸8</sup>.0¹³<sup>13,¹⁸18</sup>]icos-17-en-16-one
| image = Algestone acetonide.svg
| width = 225px
 
<!--Clinical data-->
| tradename =
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B / C / D / X -->
| pregnancy_category =
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
Line 17 ⟶ 19:
| legal_US =
| legal_status =
| routes_of_administration =
| class = [[Progestin]]; [[Progestogen]]
 
<!--Pharmacokinetic data-->
Line 24 ⟶ 27:
| metabolism =
| elimination_half-life =
| excretion =
 
<!--Identifiers-->
Line 41 ⟶ 44:
| ChEBI = 49320
| KEGG = D02808
| synonyms = W-3395; Alfasone acetonide,; alphasoneAlphasone acetonide; Algestone 16α,17α-acetonide; 16α,17α-Isopropylidenedioxyprogesterone; 16α,17α-(isopropylidenedioxyIsopropylidenedioxy)pregn-4-ene-3,20-dione▼
 
<!--Chemical data-->
| C=24 | H=34 | O=4
| smilesSMILES = CC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(CC[C@H]4[C@H]3CCC5=CC(=O)CC[C@]45C)C)OC(O2)(C)C▼
| molecular_weight = 386.52436 g/mol
▲| smiles = CC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(CC[C@H]4[C@H]3CCC5=CC(=O)CC[C@]45C)C)OC(O2)(C)C
| StdInChI_Ref =
| StdInChI = 1S/C24H34O4/c1-14(25)24-20(27-21(2,3)28-24)13-19-17-7-6-15-12-16(26)8-10-22(15,4)18(17)9-11-23(19,24)5/h12,17-20H,6-11,13H2,1-5H3/t17-,18+,19+,20-,22+,23+,24-/m1/s1
| StdInChIKey_Ref =
| StdInChIKey = LSWBQIAZNGURQV-WTBIUSKOSA-N
▲| synonyms = Alfasone acetonide, alphasone acetonide; 16α,17α-(isopropylidenedioxy)pregn-4-ene-3,20-dione
}}
 
'''Algestone acetonide''' ([[United States Adopted Name|USAN]], [[British Approved Name|BAN]]) (developmental code name '''W-3395'''), also known as '''algestone 16α,17α-acetonide''' or '''16α,17α-isopropylidenedioxyprogesterone''', is a [[steroid]]al [[progestin]] thatwhich was never marketed.<ref name="Elks2014">{{cite book |author vauthors =J. Elks J |title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA27|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=27–}}</ref><ref name="MortonHall2012">{{cite book|author1 vauthors =I.K. Morton|author2=Judith M.IK, Hall JM |title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA10|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4439-1|pages=10–}}</ref> It is the [[acetonide]] [[cyclic compound|cyclic]] [[ketal]] of [[algestone]].<ref name="Elks2014" /><ref name="MortonHall2012" /> Another progestin, [[algestone acetophenide]], in contrast, has been marketed.<ref name="Elks2014" /><ref name="MortonHall2012" />
 
==See alsoChemistry==
{{See also|List of progestogens|List of progestogen esters#Cyclic ketals of progesterone derivatives}}
▲* [[Algestone acetophenide]]
 
==References==
{{Reflist|30em}}
 
{{Progesterone receptor modulators}}
 
[[Category:Abandoned drugs]]
{{DEFAULTSORT:Algestone Acetonide}}
 
[[Category:Acetonides]]
[[Category:Diketones]]
[[Category:Pregnanes]]
[[Category:Progestogens]]
[[Category:Steroid cyclic ketals]]
 
 
{{genito-urinary-drug-stub}}
{{systemic-hormonal-drug-stub}}
{{steroid-stub}}
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