File:Apoptosis induced by scFV 4D5-dibarnase.jpg

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Captions

Captions

see membrane blebbing under a microscope.

Summary

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Description
English: SKOV-3 cells treated with scFv 4D5-dibarnase for 72 h demonstrated membrane blebbing. (A) The mock-treated cells were attached to the plate and were flat. (B) Cells incubated with 50 nM scFv 4D5-dibarnase became rounded and detached. Membrane blebbing (asterisks) were observed. Phase-contrast microscopy of a random field at a magnification of 400×.
Українська: Апоптична морфрофологія клітин SKOV-3 оброблених scFv 4D5-дибарназою впродовж 72 годин. (А) У контролі клітини плоскі і приєднані до поверхні. (B) Клітини оброблені 50 нМ scFv 4D5-дибарназою округлились і від'єднались від субстрату. Зірочками позначене утворення мембранних бульбашок. Фазовоконтрастна мікроскопія випадкового поля, збільшення 400x.
Date
Source Modified from Edelweiss E, Balandin TG et al Barnase as a New Therapeutic Agent Triggering Apoptosis in Human Cancer Cells PLoS One. 2008 Jun 18;3(6):e2434.
Author Edelweiss E, Balandin TG, Ivanova JL, Lutsenko GV, Leonova OG, Popenko VI, Sapozhnikov AM, Deyev SM

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PLOS
PLOS
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