File:Биосинтез и регенерация тетрагидробиоптерина (BH4) и выполняемые им функции.png

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Русский: Упрощенная схема биосинтеза и регенерации тетрагидробиоптерина (BH4) в пресинаптическом окончании аксона. BH4 является незаменимым кофактором таких гидроксилаз ароматических аминокислот, как фенилаланингидроксилаза (ФАГ), тирозингидроксилаза (ТГ) и триптофангидроксилаза (ТФГ) – они катализируют важные реакции в цепочках синтеза таких моноаминов, как дофамин, серотонин, норадреналин и адреналин. На рисунке не представлена алкилглицеролмонооксигеназа (AGMO) и синтазы оксида азота (NO-синтазы). 5-ГИУК, 5-гидроксииндолуксусная кислота; 5-ГИАА, 5-гидроксииндолацетальдегид; 7,8-BH2, 7,8-дигидробиоптерин; BH4, тетрагидробиоптерин; ДФУК, 3,4-дигидроксифенилуксусная кислота; ДФАА, 3,4-дигидроксифенилацетальдегид; СНТД, синдром недостаточности транспортера дофамина; ГТФ, гуанозин-5′-трифосфат; ГВК, гомованилиновая кислота; Оксо-PH4, оксо-2-гидрокси-тетрагидробиоптерин; ПОФ, пиридоксаль 5′-фосфат; ПТП, 6-пирувоилтетрагидроптерин; qBH2, хиноидная форма дигидробиоптерина; ВМоК, ваниллактовая кислота; ВМК, ванилилминдальная кислота; ВТМ-2, везикулярный транспортер моноаминов. Из консенсусного руководства по недостаточности тетрагидробиоптерина, 2020 год.
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Source https://ojrd.biomedcentral.com/articles/10.1186/s13023-020-01379-8
Author Thomas Opladen, Eduardo López-Laso, Elisenda Cortès-Saladelafont, Toni S. Pearson, H. Serap Sivri, Yilmaz Yildiz, Birgit Assmann, Manju A. Kurian, Vincenzo Leuzzi, Simon Heales, Simon Pope, Francesco Porta, Angeles García-Cazorla, Tomáš Honzík, Roser Pons, Luc Regal, Helly Goez, Rafael Artuch, Georg F. Hoffmann, Gabriella Horvath, Beat Thöny, Sabine Scholl-Bürgi, Alberto Burlina, Marcel M. Verbeek, Mario Mastrangelo, Jennifer Friedman, Tessa Wassenberg, Kathrin Jeltsch, Jan Kulhánek & Oya Kuseyri Hübschmann

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Date/TimeThumbnailDimensionsUserComment
current08:04, 21 April 2021Thumbnail for version as of 08:04, 21 April 20211,946 × 1,835 (3.78 MB)CopperKettle (talk | contribs)Reverted to version as of 07:33, 21 April 2021 (UTC) because the missing sign I added appeared in the box. I thought I bungled the re-upload, and did that twice
07:35, 21 April 2021Thumbnail for version as of 07:35, 21 April 20211,946 × 1,835 (3.78 MB)CopperKettle (talk | contribs)Added a missing sign
07:33, 21 April 2021Thumbnail for version as of 07:33, 21 April 20211,946 × 1,835 (3.78 MB)CopperKettle (talk | contribs)I forgot to add the sign "phenylalanine" in one of the boxes. Now fixed.
09:05, 14 April 2021Thumbnail for version as of 09:05, 14 April 20211,946 × 1,835 (3.78 MB)CopperKettle (talk | contribs)I forgot to translate one abbreviation into Russian - now did that.
08:50, 14 April 2021Thumbnail for version as of 08:50, 14 April 20211,946 × 1,835 (3.78 MB)CopperKettle (talk | contribs)Uploaded a work by Thomas Opladen, Eduardo López-Laso, Elisenda Cortès-Saladelafont, Toni S. Pearson, H. Serap Sivri, Yilmaz Yildiz, Birgit Assmann, Manju A. Kurian, Vincenzo Leuzzi, Simon Heales, Simon Pope, Francesco Porta, Angeles García-Cazorla, Tomáš Honzík, Roser Pons, Luc Regal, Helly Goez, Rafael Artuch, Georg F. Hoffmann, Gabriella Horvath, Beat Thöny, Sabine Scholl-Bürgi, Alberto Burlina, Marcel M. Verbeek, Mario Mastrangelo, Jennifer Friedman, Tessa Wassenberg, Kathrin Jeltsch, Jan...

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