1.
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High Sensitivity and High Resolution Dynamic Brain-Dedicated TOF-DOI PET Scanner
/ Bläckberg, L (Harvard Medical School) ; Sanchez, D (ICC, Barcelona U.) ; Borghi, G (ICC, Barcelona U.) ; Ballabriga, R (CERN) ; Sajedi, S (Stanford U., Med. School) ; Gómez, S (ICC, Barcelona U.) ; El Fakhri, G (Harvard Medical School) ; Mazzi, A (Fond. Bruno Kessler, Trento) ; Paternoster, G (Fond. Bruno Kessler, Trento) ; Majewski, S (UC, Davis) et al.
We are presenting a novel design of a high performance brain dedicated PET scanner which focuses on optimizing imaging performance in the whole brain, as well as in head and neck, through simultaneous high resolution and high sensitivity. This is realized using a sensitivity-optimized scanner design composed of an elliptical cylinder that follows the shape of the human head, together with added front and back panels for increased coverage. [...]
2020 - 5 p.
- Published in : 10.1109/NSS/MIC42677.2020.9507837
In : 2020 IEEE Nuclear Science Symposium (NSS) and Medical Imaging Conference (MIC), Boston, United States, 31 Oct - 7 Nov 2020
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2.
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State of the art timing in TOF-PET detectors with LuAG, GAGG and L(Y)SO scintillators of various sizes coupled to FBK-SiPMs
/ Gundacker, S. (CERN) ; Acerbi, F. (Fond. Bruno Kessler, Trento) ; Auffray, E. (CERN) ; Ferri, A. (Fond. Bruno Kessler, Trento) ; Gola, A. (Fond. Bruno Kessler, Trento) ; Nemallapudi, M.V. (CERN) ; Paternoster, G. (Fond. Bruno Kessler, Trento) ; Piemonte, C. (Fond. Bruno Kessler, Trento) ; Lecoq, P. (CERN)
Time of flight (TOF) in positron emission tomography (PET) has experienced a revival of interest after its first introduction in the eighties. This is due to a significant progress in solid state photodetectors (SiPMs) and newly developed scintillators (LSO and its derivatives). [...]
2016
- Published in : JINST 11 (2016) P08008
IOP Open Access article: PDF;
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3.
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Performance evaluation of the FastIC readout ASIC with emphasis on Cherenkov emission in TOF-PET
/ Piller, Markus (CERN ; Graz U.) ; Castilla, Antonio M (Barcelona U.) ; Terragni, Giulia (CERN ; Vienna, Tech. U.) ; Alozy, Jerome (CERN) ; Auffray, Etiennette (CERN) ; Ballabriga, Rafael (CERN ; Barcelona U.) ; Campbell, Michael (CERN) ; Deutschmann, Bernd (Graz U.) ; Gascon, David (Barcelona U.) ; Gola, Alberto (Fond. Bruno Kessler, Trento) et al.
Objective. The efficient usage of prompt photons like Cherenkov emission is of great interest for the design of the next generation, cost-effective, and ultra-high-sensitivity time-of-flight positron emission tomography (TOF-PET) scanners. [...]
2024 - 13 p.
- Published in : Phys. Med. Biol. 69 (2024) 115014
Fulltext: PDF;
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4.
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Optimizing time resolution and power consumption in a current-mode circuit for SiPMs
/ Manera, R (ICC, Barcelona U.) ; Gómez, S (Barcelona, Polytechnic U. ; ICC, Barcelona U.) ; Mariscal-Castilla, A (ICC, Barcelona U.) ; Mauricio, J (ICC, Barcelona U.) ; Ballabriga, R (CERN) ; Gascón, D (ICC, Barcelona U.)
Several applications that employ SiPMs require high time precision readout electronics. This work presents a study for the optimization of timing resolution of readout electronics for SiPMs focused on the effect of sensor area, transistor scaling and power consumption on electronic jitter. [...]
2024 - 21 p.
- Published in : JINST 19 (2024) T04009
Fulltext: PDF;
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5.
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Design considerations for a new generation of SiPMs with unprecedented timing resolution
/ Enoch, S. (Fresnel Inst., Marseille) ; Gola, A. (Fond. Bruno Kessler, Trento) ; Lecoq, P. (CERN ; Valencia, Polytechnic U.) ; Rivetti, A. (Turin U.)
The potential of photon detectors to achieve precise timing information is of increasing importance in many domains, PET and CT scanners in medical imaging and particle physics detectors, amongst others. The goal to increase by an order of magnitude the sensitivity of PET scanners and to deliver, via time-of-flight (TOF), true space points for each event, as well as the constraints set by future particle accelerators require a further leap in time resolution of scintillator-based ionizing radiation detectors, reaching eventually a few picoseconds resolution for sub MeV energy deposits. [...]
arXiv:2101.02952.-
2021-02-12 - 16 p.
- Published in : JINST 16 (2021) P02019
Fulltext: PDF; Fulltext from publisher: PDF;
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6.
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FastIC ASIC readout performance for Cherenkov based TOF-PET imaging
/ Piller, M (CERN ; Graz U.) ; Mariscal-Castilla, A (Barcelona U.) ; Terragni, G (CERN ; TU Vienna) ; Penna, M (Fond. Bruno Kessler, Trento) ; Merzi, S (Fond. Bruno Kessler, Trento) ; Moretti, E (Fond. Bruno Kessler, Trento) ; Gola, A (Fond. Bruno Kessler, Trento) ; Michalowska-Forsyth, A (Graz, Tech. U.) ; Gascon, D (Barcelona U.) ; Ballabriga, R (CERN) et al.
The emerging field of ultra-fast timing has enormous potential in high-energy physics, nuclear medicine, and imaging, and is driving advances in detector and readout electronics. To achieve improved time resolution, significant efforts have been devoted to this field, resulting in impressive coincidence time resolution (CTR) values for silicon photomultiplier (SiPM) and scintillator crystals using state-of-the-art high-frequency (HF) readout. [...]
2023 - 1 p.
- Published in : 10.1109/NSSMICRTSD49126.2023.10337861
In : 2023 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector (RTSD) Conference (2023 IEEE NSS MIC RTSD), Vancouver, Canada, 4 - 11 Nov 2023
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7.
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Development of a high resolution module for PET scanners
/ Stringhini, G (CERN ; Milan Bicocca U.) ; Pizzichemi, M (Milan Bicocca U.) ; Ghezzi, A (Milan Bicocca U.) ; Stojkovic, A (Wellesley Coll.) ; Tavernier, S (LIP, Lisbon ; Vrije U., Brussels) ; Niknejad, T (LIP, Lisbon) ; Varela, J (LIP, Lisbon) ; Paganoni, M (Milan Bicocca U.) ; Auffray, E (CERN)
Positron Emission Tomography (PET) scanners require high performances in term of spatial resolution and sensitivity to allow early detection of cancer masses. In small animal and organ dedicated PET scanners the Depth of Interaction (DOI) information has to be obtained to avoid parallax errors and to reconstruct high resolution images. [...]
2017 - 8 p.
- Published in : JINST 12 (2017) C02073-C02073
In : 14th Topical Seminar on Innovative Particle and Radiation Detectors , Siena, Italy, 3 - 6 Oct 2016, pp.C02073-C02073
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8.
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The AX-PET experiment: A demonstrator for an axial Positron Emission Tomograph
/ Bolle, E (Oslo U.) ; Casella, C (Zurich, ETH) ; Chesi, E (Ohio State U.) ; De Leo, R (INFN, Bari) ; Dissertori, G (Zurich, ETH) ; Fanti, V (INFN, Cagliari ; Cagliari U.) ; Gillam, J.E (Valencia U., IFIC) ; Heller, M (CERN) ; Joram, C (CERN) ; Lustermann, W (Zurich, ETH) et al.
AX-PET stands for a new geometrical concept for a high resolution and high sensitivity PET scanner, based on an axial arrangement of long scintillating crystals in the tomograph, for a parallax free PET detector. Two identical AX-PET modules - consisting of matrices of LYSO crystals interleaved with WLS strips - have been built. [...]
2013 - 4 p.
- Published in : Nucl. Instrum. Methods Phys. Res., A 718 (2013) 126-129
In : 12th Pisa Meeting on Advanced Detectors: Frontier Detector for Frontier Physics, La Biodola, Isola d'Elba, Italy, 20 - 26 May 2012, pp.126-129
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9.
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Sub-100 ps coincidence time resolution for positron emission tomography with LSO:Ce codoped with Ca
/ Nemallapudi, Mythra Varun (CERN) ; Gundacker, Stefan (CERN) ; Lecoq, Paul (CERN) ; Auffray, Etiennette (CERN) ; Ferri, Alessandro (Fond. Bruno Kessler, Trento) ; Gola, Alberto (Fond. Bruno Kessler, Trento) ; Piemonte, Claudio (Fond. Bruno Kessler, Trento)
The coincidence time resolution (CTR) becomes a key parameter of 511keV gamma detection in time of flight positron emission tomography (TOF-PET). This is because additional information obtained through timing leads to a better noise suppression and therefore a better signal to noise ratio in the reconstructed image. [...]
2015 - 15 p.
- Published in : Phys. Med. Biol. 60 (2015) 4635-4649
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10.
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Vacuum ultraviolet silicon photomultipliers applied to BaF$_2$ cross-luminescence detection for high-rate ultrafast timing applications
/ Gundacker, S (CERN ; Milan Bicocca U.) ; Pots, R H (CERN ; Aachen, Tech. Hochsch.) ; Nepomnyashchikh, A (Irkutsk State U.) ; Radzhabov, E (Irkutsk State U.) ; Shendrik, R (Irkutsk State U.) ; Omelkov, S (Tartu, Inst. Phys.) ; Kirm, M (Tartu, Inst. Phys.) ; Acerbi, F (Fond. Bruno Kessler, Povo) ; Capasso, M (Fond. Bruno Kessler, Povo) ; Paternoster, G (Fond. Bruno Kessler, Povo) et al.
Inorganic scintillators are widely used for fast timing applications in high-energy physics (HEP) experiments, time-of-flight positron emission tomography and time tagging of soft and hard x-ray photons at advanced light sources. As the best coincidence time resolution (CTR) achievable is proportional to the square root of the scintillation decay time it is worth studying fast cross-luminescence, for example in BaF2 which has an intrinsic yield of about 1400 photons/MeV. [...]
2021 - 18 p.
- Published in : Phys. Med. Biol. 66 (2021) 114002
Fulltext: PDF;
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