002812519 001__ 2812519
002812519 003__ SzGeCERN
002812519 005__ 20220617211049.0
002812519 0247_ $$2DOI$$a10.1038/s41598-020-80463-2
002812519 0248_ $$aoai:cds.cern.ch:2812519$$pcerncds:FULLTEXT$$pcerncds:CERN:FULLTEXT$$pcerncds:CERN
002812519 035__ $$9https://inspirehep.net/api/oai2d$$aoai:inspirehep.net:2075807$$d2022-06-16T07:35:28Z$$h2022-06-17T04:03:14Z$$mmarcxml
002812519 035__ $$9Inspire$$a2075807
002812519 041__ $$aeng
002812519 100__ $$aLau, Lawrence Chun Man$$uHong Kong, Chinese U.
002812519 245__ $$9submitter$$aMulti-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
002812519 260__ $$c2021
002812519 300__ $$a6 p
002812519 520__ $$9submitter$$aTo determine whether state-of-the-art multi-energy spectral photon-counting computed tomography
(MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging
techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted
prosthesis [NexGen Legacy Posterior Stabilized (LPS) TKA] was analyzed as were pre-operative
imaging examination and compared with a MARS-CT examination obtained of the extracted TKA
prosthesis. Radiographs, fuoroscopy, ultrasound and MRI preoperatively did not reveal the cause
of the implant failure. MARS CT images of the extracted prosthesis clearly showed the presence of
posteromedial polyethylene and tibial tray wear which is compatible with the clinical appearance of
the extracted TKA. MARS can identify polyethylene insert and metallic tibial tray wear as a cause of
TKA failure, that could not be identifed with on standard pre-operative imaging. Although clinical
MARS CT system is still under development, this case does illustrate its potential clinical usefulness.
This is the frst study to document how MARS CT imaging can detect orthopedic implant failure not
detected by standard current imaging techniques. This system has a potential clinical application in
orthopedic patients.
002812519 540__ $$aCC-BY-4.0$$uhttp://creativecommons.org/licenses/by/4.0/
002812519 542__ $$dThe Author(s)$$g2021
002812519 65017 $$2SzGeCERN$$aPhysics in General
002812519 690C_ $$aARTICLE
002812519 690C_ $$aCERN
002812519 700__ $$aLee, Wayne Yuk Wai$$uHong Kong, Chinese U.$$vLi Ka Shing Institute of Health Sciences, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
002812519 700__ $$aButler, Anthony P H$$uOtago U.$$uCanterbury U.$$uCERN$$uMARS Bioimaging$$vSchool of Physical and Chemical Sciences, University of Canterbury, Private Bag 4800, Christchurch 8140, New Zealand.$$vMARS Bioimaging Ltd, 29a Clyde Rd, Christchurch, New Zealand.
002812519 700__ $$aChernoglazov, Alex I$$uMARS Bioimaging
002812519 700__ $$aChung, Kwong Yin$$uHong Kong, Chinese U.
002812519 700__ $$aHo, Kevin Ki Wai$$uHong Kong, Chinese U.
002812519 700__ $$aGrifth, James$$uHong Kong, Chinese U.
002812519 700__ $$aButler, Philip H$$uCanterbury U.$$uCERN$$uMARS Bioimaging$$vThe European Organization for Nuclear Research (CERN), Geneva, Switzerland.
002812519 700__ $$aYung, Patrick Shu Hang$$uHong Kong, Chinese U.
002812519 773__ $$c1554$$n1$$pSci. Rep.$$v11$$y2021
002812519 8564_ $$82373162$$s1161195$$uhttps://cds.cern.ch/record/2812519/files/s41598-020-80463-2.pdf$$yFulltext
002812519 960__ $$a13
002812519 980__ $$aARTICLE