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Title Measurement of PET isotope production cross sections for protons and carbon ions on carbon and oxygen targets for applications in particle therapy range verification
Author(s) Horst, Felix (Darmstadt, GSI ; Mittelhessen U., Giessen) ; Adi, Wihan (Mittelhessen U., Giessen ; Giessen U.) ; Aricò, Giulia (CERN) ; Brinkmann, Kai-Thomas (Giessen U.) ; Durante, Marco (Darmstadt, GSI ; Darmstadt, Tech. U.) ; Reidel, Claire-Anne (Darmstadt, GSI ; Strasbourg, IPHC) ; Rovituso, Marta (TIFPA-INFN, Trento ; Unlisted, NL) ; Weber, Uli (Darmstadt, GSI) ; Zaunick, Hans-Georg (Giessen U.) ; Zink, Klemens (Frankfurt U., FIAS ; Mittelhessen U., Giessen ; U. Hospital, Giessen-Marburg) ; Schuy, Christoph (Darmstadt, GSI)
Publication 2019
Number of pages 16
In: Phys. Med. Biol. 64 (2019) 205012
DOI 10.1088/1361-6560/ab4511
Subject category Other
Abstract Measured cross sections for the production of the PET isotopes , and from carbon and oxygen targets induced by protons (40–220 ) and carbon ions (65–430 ) are presented. These data were obtained via activation measurements of irradiated graphite and beryllium oxide targets using a set of three scintillators coupled by a coincidence logic. The measured cross sections are relevant for the PET particle range verification method where accurate predictions of the emitter distribution produced by therapeutic beams in the patient tissue are required. The presented dataset is useful for validation and optimization of the nuclear reaction models within Monte Carlo transport codes. For protons the agreement of a radiation transport calculation using the measured cross sections with a thick target PET measurement is demonstrated.
Copyright/License publication: © 2019 Institute of Physics and Engineering in Medicine (License: CC-BY-3.0)

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 Record created 2019-11-09, last modified 2019-11-27


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