Urbach–Wiethe disease is inherited in an autosomal recessive manner. Urbach–Wiethe disease is a very rare recessive genetic disorder, with approximately 400 reported cases since its discovery.[1][2][3] It was first officially reported in 1929 by Erich Urbach and Camillo Wiethe,[4][5] although cases may be recognized dating back as early as 1908.[6][7][8] The symptoms of the disease vary greatly fr