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“Particle therapy - future for the Baltic states?” – synthesis of the expert workshop report
/ Paļskis, Kristaps (Riga Tech. U. ; CERN) ; Korobeinikova, Erika ; Bogorada-Saukuma, Dace ; Camarda, Anna Maria (CNAO, Milan) ; Taylor, Rebecca (CERN ; Imperial Coll., London) ; Benedetto, Elena ; Mamis, Edgars (CERN ; Latvia U.) ; Radziņa, Maija ; Ērglis, Andrejs (Latvia U.) ; Adliene, Diana et al.
Background Baltic States remains one of the few regions in the Europe without a dedicated particle therapy center. An initiative since 2021 has been started by CERN Baltic Group on a novel particle therapy center development in the region in partnership with CERN NIMMS collaboration. [...]
2024 - 8 p.
- Published in : Health Technol. 14 (2024) 965-972
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Conceptual design of a compact synchrotron-based facility for cancer therapy and biomedical research with helium and proton beams
/ Vretenar, M (CERN) ; Angoletta, M E (CERN) ; Borburgh, J (CERN) ; Bottura, L (CERN) ; Taylor, R (CERN) ; Tranquille, G (CERN) ; Benedetto, E (Unlisted, CH) ; Torims, T (Latvia U., ISSP) ; Paļskis, K (Latvia U., ISSP) ; Sapinski, M (PSI, Villigen) et al.
Thanks to their superior dose conformality and higher radiobiological effectiveness with respect to protons, helium ions are considered as the new tool of choice in the fight against cancer using particle beams. A facility to produce helium beams at therapeutical energy can also accelerate protons, at energies permitting both standardised treatment and full body radiography, and heavier ions for treatment of shallow tumours and for research. [...]
2023
- Published in : JACoW IPAC 2023 (2023) THPM058
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In : 14th International Particle Accelerator Conference (IPAC 2023), Venice, Italy, 7 - 12 May 2023, pp.THPM058
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CONCEPTUAL DESIGN OF A COMPACT SYNCHROTRON-BASED FACILITY FOR CANCER THERAPY AND BIOMEDICAL RESEARCH WITH HELIUM AND PROTONS BEAMS
/ Vretenar, Maurizio (CERN) ; Angoletta, Maria Elena (CERN) ; Borburgh, Jan (CERN) ; Bottura, Luca (CERN) ; Taylor, Rebecca (Imperial College (GB)) ; Tranquille, Gerard Alain (CERN) ; Benedetto, Elena (SEEIIST Association (CH)) ; Torims, Toms (Riga Technical University (LV)) ; Palskis, Kristaps (Riga Technical University (LV)) ; Sapinski, Mariusz (Paul Scherrer Institute (CH)) et al.
Thanks to their superior dose conformality and higher radiobiological effectiveness with respect to protons, helium ions are considered as the new tool of choice in the fight against cancer using particle beams [...]
CERN-ACC-NOTE-2023-0012 ; NIMMS-Note-018.
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2023. - 6 p.
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Novel radionuclides for use in Nuclear Medicine in Europe: where do we stand and where do we go?
/ Radzina, Maija (Latvia U. ; CERN) ; Saule, Laura (Latvia U.) ; Mamis, Edgars (Latvia U. ; CERN) ; Koester, Ulli (Laue-Langevin Inst.) ; Cocolios, Thomas Elias (Leuven U.) ; Pajuste, Elina (Latvia U.) ; Kalnina, Marika (Unlisted) ; Palskis, Kristaps (CERN ; Riga Tech. U.) ; Sawitzki, Zoe (Leuven U.) ; Talip, Zeynep (PSI, Villigen) et al.
Background
In order to support the ongoing research across Europe to facilitate access to novel radionuclides, the PRISMAP consortium (European medical radionuclides programme) was established to offer the broadest catalog of non-conventional radionuclides for medical and translational research. The aim of this article is to introduce readers with current status of novel radionuclides in Europe.
Main body
A consortium questionnaire was disseminated through the PRISMAP consortium and user community, professional associations and preclinical/clinical end users in Europe and the current status of clinical end-users in nuclear medicine were identified. [...]
2023 - 16 p.
- Published in : EJNMMI Radiopharm. Chem. 8 (2023) 27
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Scandium thermal release from activated natTi and natV target materials in mixed particle fields: Investigation of parameters relevant for isotope mass separation
/ Mamis, E (CERN ; Latvia U.) ; Kalnina, P (CERN ; Latvia U.) ; Duchemin, C (CERN) ; Lambert, L (CERN) ; Conan, N (CERN) ; Deschamps, M (CERN) ; Dorsival, A (CERN) ; Froeschl, R (CERN) ; Ruiz, F Ogallar (CERN) ; Theis, C (CERN) et al.
Scandium (Sc) has gained significant interest in nuclear medicine due to its 43Sc, 44g/mSc, and 47Sc radioactive isotopes being suitable for cancer diagnostics and therapy, offering a promising avenue for theranostics. Various production methods, including irradiation of enriched or naturally abundant calcium (Ca), titanium (Ti), and vanadium (V) materials with different particle beams, have been investigated to produce 43Sc, 44g/mSc, and 47Sc. [...]
2024 - 10 p.
- Published in : Nucl. Instrum. Methods Phys. Res., B 553 (2024) 165400
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Metal additive manufacturing for particle accelerator applications
/ Romano, Tobia (Milan, Polytech. ; Riga Tech. U.) ; Pikurs, Guntis (CERN ; Riga Tech. U.) ; Ratkus, Andris (Riga Tech. U.) ; Torims, Toms (CERN ; Riga Tech. U.) ; Delerue, Nicolas (IJCLab, Orsay) ; Vretenar, Maurizio (CERN) ; Stepien, Lukas (Fraunhofer Inst., Dresden) ; López, Elena (Fraunhofer Inst., Dresden) ; Vedani, Maurizio (Milan, Polytech.)
Metal additive manufacturing technologies are rapidly becoming an integral part of the advanced technological portfolio for the most demanding industrial applications. These processes are capable of fabricating three-dimensional components with near-net shape quality by depositing the constituent materials in a layer-by-layer fashion. [...]
2024 - 38 p.
- Published in : Phys. Rev. Accel. Beams 27 (2024) 054801
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Target Development towards First Production of High-Molar- Activity $^{44g}$Sc and $^{47}$Sc by Mass Separation at CERN-MEDICIS
/ Mamis, Edgars (CERN ; Latvia U.) ; Duchemin, Charlotte (CERN) ; Berlin, Valentina (CERN) ; Bernerd, Cyril (CERN) ; Bovigny, Mathieu (CERN) ; Chevallay, Eric (CERN) ; Crepieux, Bernard (CERN) ; Gadelshin, Vadim Maratovich (Mainz U., Inst. Phys.) ; Heinke, Reinhard (CERN) ; Hernandez, Ronaldo Mendez (CERN ; Havana, ISCTN) et al.
The radionuclides 43Sc, 44g/mSc, and 47Sc can be produced cost-effectively in sufficient yield for medical research and applications by irradiating natTi and natV target materials with protons. Maximizing the production yield of the therapeutic 47Sc in the highest cross section energy range of 24–70 MeV results in the co-production of long-lived, high-γ-ray-energy 46Sc and 48Sc contaminants if one does not use enriched target materials. [...]
2024 - 28 p.
- Published in : Pharmaceuticals 17 (2024) 390
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Union of light ion therapy centers in Europe (ULICE EC FP7) – Objectives and achievements of joint research activities
/ Pötter, Richard (Med. U. of Vienna, Spitalgasse) ; Balosso, Jaques (U. Grenoble Alpes ; Centre Hospitalier Universitaire Grenoble Alpes) ; Baumann, Michael (OncoRay, Dresden ; TU, Dresden (main) ; HZDR, Dresden ; DKTK, Dresden ; Heidelberg, Inst. Radiology) ; Bert, Christoph (U. Erlangen-Nuremberg (main)) ; Davies, Jim (U. Oxford (main)) ; Enghardt, Wolfgang (OncoRay, Dresden ; TU, Dresden (main) ; HZDR, Dresden ; DKTK, Dresden ; Heidelberg, Inst. Radiology) ; Fossati, Piero (EBG MedAustron GmbH, Wiener Neustadt) ; Harris, Steve (U. Oxford (main)) ; Jones, Bleddyn (U. Oxford (main)) ; Krämer, Michael (Darmstadt, GSI) et al.
/ULICE
Under the umbrella of the European Network for Light Ion Therapy (ENLIGHT), the project on Union of Light Ion Centers in Europe (ULICE), which was funded by the European Commission (EC/FP7), was carried out from 2009 to 2014. Besides the two pillars on Transnational Access (TNA) and Networking Activities (NA), six work packages formed the pillar on Joint Research Activities (JRA). [...]
2018 - 18 p.
- Published in : Radiotherapy Oncology 128 (2018) 83-100
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